Thread by @firefoxx66

Huge thanks to @HopkinsMedicine @AmaryFaln @hmostaf2 for sending along the first #Enterovirus #D68 #EVD68 sequences of 2022! 🙏🏻🚀

You can see them in the full-genome & VP1 builds:
nextstrain.org/enterovirus/d6…
nextstrain.org/enterovirus/d6…

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Note that for the moment I don't have anything but year for these sequences, so month is being inferred by the pipeline - note the wide confidence interval on the date!

However, zooming into the VP1 build, we can see some interesting connections...

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All part of the B3 clade, 1 seq attaches to autumn 2021 circulation in Europe/USA (1), 1 attaches back to European circulation in autumn 2019 (2), and the rest attach back to USA+ circulation in autumn 2019 (3).

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Comparing to the full-genome build, where we have fewer sequences, you can see that such interesting connections aren't visible! This is why I maintain both builds - different strengths! 😁

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Data for most viruses, including #EVD68, doesn't come through as fast as for #SARSCoV2, but as we continue to receive more samples, we'll gain additional insights into what's changed & what's the same pre- and post-pandemic restrictions.

Thanks to everyone who shares seqs!

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