1. Two fascinating reports from 2 different @CDCgov journals today on #monkeypox acquisition via needlestick injuries. The takeaway message for me: If you are a HCP & you have a sharps injury involving MPX, you probably want to get vaccinated right away.
2. The first report came out in #MMWR. A Florida nurse who was using a syringe to extract fluid from a suspected #monkeypox lesion pricked her finger, drawing blood. She got the first of 2 doses of Jynneos within 15 hours & only developed 1 lesion. cdc.gov/mmwr/volumes/7…
3. The 2nd report, in @EIDjournal, is about a Portuguese doctor who had a similar needlestick injury while sampling a suspected #monkeypox lesion. There was no bleeding, he thought his glove was intact, and he didn't report the exposure. He was not vaccinated.
4. When the Portuguese doctor developed his first #monkeypox lesion — at the site of the injury — it was determined it was too late to vaccinate. He went on to have lesions on his scalp, neck, forearm, both hands, ankle and scrotum. wwwnc.cdc.gov/eid/article/28…
5. Another takeaway, highlighted in the @EIDjournal article, is that people shouldn't be using sharps to sample #monkeypox lesions.
This is the 3rd such report I've seen. There was another published last month in @EIDjournal, from Brazil. wwwnc.cdc.gov/eid/article/28…

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More from @HelenBranswell

Oct 19
1. Short thread from @WHO's weekly press conference. Covid-19 remains a Public Health Emergency of International Concern (PHEIC), the @WHO emergency committee decided at a meeting last week. Today @DrTedros said he agrees.
2. The EC chair, Didier Houssin, said for the first time at this meeting, the committee talked about the possibility of terminating the PHEIC. But the committee concluded it was too early to do so. Among other things, they want to see how this winter goes in the NHemisphere.
3. @DrTedros revealed that @WHO and partners have decided to effectively ration #Cholera vaccines, because of a global shortage. Normally cholera vax is given in 2 doses but will be used as a 1 dose vaccine. This strategy has been shown to be effective before.
Read 10 tweets
Oct 19
1. #ACIP is meeting today & tomorrow. This is one of their 3 scheduled meetings that take place every year.
There will be some discussion of Covid vaccines today, but this meeting will not be primarily about Covid vaccines. Lots of items on this agenda. cdc.gov/vaccines/acip/…
2. I will NOT be live tweeting much in this meeting. When I do tweet, I will do it in this thread.
There are not going to be many votes during these 2 days. Many of the sessions will be about informing #ACIP members on vaccines in development (eg. chikungunya).
3. There'll be a vote about adding Covid vaxes to the Vaccines for Children program. With federal money for Covid all but exhausted, the full cost of future boosters will be paid by individuals or their insurance. This is about ensuring kids without insurance can get vaxed. #ACIP
Read 8 tweets
Oct 14
1. A short #flu update:
@CDCgov has posted the FluView report for the week ending Oct. 8. It is the first FluView report for the 2022-23 flu season.
Flu activity is ticking up a bit, especially in the southeast and southcentral parts of the US.
2. The increase in #influenza-like illness (not all #flu) seems to be most marked in young kids, which isn't much of a surprise. Little kids always catch a lot of respiratory infections; kids who were protected from them in the early part of the pandemic may catch more for awhile
3. Something I do find surprising is that #flu outbreaks in long-term care facilities are still really rare. 0.3% of LTCF reported a flu outbreak last week. Seniors are really susceptible to flu & LTC outbreaks were common in the before-times. Will be again, no doubt.
Read 4 tweets
Oct 5
1. Turning this into a short #Ebola thread:
Uganda's health ministry is producing daily or near daily situation reports (I've seen some), but they are not being released to the media, as far as I can tell. It's been challenging finding up to date data on what's going on there.
2. There have been at least 10 #Ebola infections in health workers. To date 4 have died. The following info comes from the twitter account of Uganda's health minister. The deceased are: Ms. Nabisubi Margaret, an anesthetic officer; Dr Mohammed Ali; an unnamed midwife and ...
3. ...and an unnamed health assistant in Kagadi District. Tragic losses.
Cases have been reported in at least 5 districts in the country.
I am not sure at this point how many confirmed & probable cases there have been. Between 61 or 63, I think. I think there've been ~30 deaths
Read 5 tweets
Oct 1
1. Does it feel like we're seeing far more filovirus outbreaks (#Ebola, #Marburg) in recent years? It does to me so I plotted outbreaks into a graph. No lab accident cases, or outbreaks with only lab animals, ie 1967 Marburg. Each outbreak is only counted on the year it started. Image
2. Likewise, I didn't count spread to other countries as distinct outbreaks, like the #Ebola cases in Spain, the US & Nigeria, etc from the 2014 West African outbreak.
So it definitely feels like #Ebola & #Marburg outbreaks have been more frequent since the mid-1990s. Image
3. Some of that increase in frequency could be real. Climate change? Better detection of outbreaks. But some of it is probably due to the fact that #Ebola outbreaks beget more Ebola outbreaks. The more Ebola survivors there are, the higher the risk of survivor-ignited cases. Image
Read 4 tweets
Sep 30
1. It's Friday, so time for a #flu 🧵
@CDCgov reports that two more kids died from #flu in the 2021-22 flu season. They died in the weeks ending July 30 & Aug. 20. Not super usual time for pediatric flu deaths. They bring the 2021-22 total to 39. Image
2. The rate of outpatient visits by kids under 4 (& to a lesser extent kids, teens & young adults aged 5-24) for a respiratory illness is ticking up. Not surprising to see. Could presage upticks in other ages.
Some of this could be #flu but lots of RSV, rhinoviruses around. Image
3. What's really interesting to me is that #flu remains at super low levels in long-term health facilities. It's been this way pretty much since the Covid pandemic took off. Flu typically takes its greatest toll on frail seniors. Image
Read 6 tweets

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