Discussing inflammatory bowel disease treatments with patients, with @tinahamd
#MedTwitter #GITwitter #IBD #ACG2022
#MedTwitter #GITwitter #IBD #ACG2022
First, need to explain #IBD itself to patients
🔌anti-TNFs "block the plug," preventing turning on the inflammatory pathways
Factors that influence PK of anti-TNFs
Adverse effects of anti-TNFs: what are they and more importantly, how can we prevent them?
Practical tips for anti-TNFs
⛔️Vedolizumab blocks lymphocytes from entering GI lumen
Adverse effects of vedolizumab
Low immunogenicity
Low immunogenicity
Practical tips for vedolizumab
🔌p19 and p40 agents: dual-pronged plug
Adverse effects of p19 and p40 agents
Low immunogenicity
Low immunogenicity
Practical tips for p19 and p40 agents
💡Great option for patients with dermatologic conditions (but not great if spondyloarthropathies)
💡Great option for patients with dermatologic conditions (but not great if spondyloarthropathies)
🀄️Jak inhibitors: prevent domino effect of inflammatory cascade
Adverse effects of Jak-inhibitors
💡Remember that active disease and steroids also ⬆️ thromboembolic risk
💡Remember that active disease and steroids also ⬆️ thromboembolic risk
Practical tips for Jak-inhibitors
💡Especially helpful in axial spondyloarthropathies
💡Use validated CVD risk scores
💡Especially helpful in axial spondyloarthropathies
💡Use validated CVD risk scores
S1P agents: a parking lot, a highway, and a target site
Adverse effects of S1Ps
Practical tips for S1Ps
What to consider when selecting #IBD treatment
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