Demographcis also change == in reference to White ethnicity, other ethnicity has higher Odds ratio (this is in keeping with higer risk for COVID in these patients)
Rhythm : also reduction in shockable rhythms and high PEA/Asystole #covid19#LIVES2022
Summary : a lot more ohca. A lot more in ethnic groups. A lot more non shockable rhythms
outcomes also much worse
- less ROSC
- less sustained ROSC
Why are we seeing these outcomes? #LIVES2022
we need to follow change of care #COVID19#ALS
pre-hospital, EMS and ED / ICU chain of care.
pre-hosp : low bystander CPR & lower use of public CPR (closed public buildings)
- non shockable rhythm probably because shockable patients deteriorate further into cardiac arrest
- paramedics were overwhelmed, EMS response times go up
- overwhelmed health care systems
- allocation of resources issues
so in summary.
outcomes got significantly worse
- lower ROSC
- lower survival to hospital
So
- need a health system based response
- e.g., CPR training + AEDs in more easily accessible public spaces
AND MOST IMPORTANT IS "STAFF"
- in ED, in Prehospitla, in ICU's #COVID19#LIVES2022
Mariangela PELLEGRINI
Uppsala- Sweden
"Do we Need a biological definition of ARDS"
- Berlin definition has NO Diffuse alveolar damage .
- the Berlin defn does not capture well
Frohlich - different definitions specificity of 0.63, 0.42, 0.31 even! #ventilation#ards#LIVES2022
ARDS - new definition or phenotypes by @GicoBellani refreshing with Kigali definition of ARDS - useful not just low resource but during pandemic in supposedly high income settings and only draw back is no PEEp requirement #ards#ventilation#LIVES2022@ESICM
@GicoBellani@ESICM Resolved versus confirmed ARDS
- prospectively applying Berlin definition did work but if ya wait 24 hrs and re-measure P/F ratio, you end up stratifying much better.
- Better separation of groups
NEXT Speaker : VA ecmo for which patients?
Alain COMBES
Severe cardiogenic shock has different phenotypes 1. medical cardiogenic shock(AMI, end stage dilated CM, myocarditis, septic shock) 2. Post cardiotomy refractory CS (post CABG) #LIVES2022 @ESICM#ecmo#resuscitation#ALS
@ESICM 2022 what do the guidelines say
- ESC recommends short term MCS should be considred in cardiogenic shock.
IABP may be considered but not routinely recommended in post MI #LIVES2022
@ESICM PARAMEDIC 2 - big study
8007 pts, adrenaline 4000, placebo 3999
- a lot of discussion post trial
- need a nuanced interpretation.
- 19 "more good" survivors and 5 "more bad" survivors in adrenaline arm.