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Dr Elisa Perego

@elisaperego78

Dec 3

There is a huge convergence of interests in presenting #LongCovid as a "fatiguing syndrome" and some "vague symptoms". This is not the case: Long Covid comes with prolonged dysfunction and injury across multiple organs and body systems. This includes the cardiovascular system

#LongCovid can affect basically all systems and organs, although with variability across individuals: liver, lung, kidney, immune system, gastrointestinal tract, blood vessels, endothelium, heart, nervous system and brain, just to name a few. We know this since 2020 and 2021

There is a huge amount of scientific evidence on acute and #LongCovid which are/is among the most studied diseases in human history. Anyone speaking of a "mysterious" disease is wrong, or not up to date with the evidence. Covid has massively accelerated research in biomedicine

Read 5 tweets

Dr Elisa Perego

@elisaperego78

Dec 2

"They have fever, dry cough, sometimes violent. The little ones, up to 1 year, may have bronchiolitis and need oxygen. We hospitalize the most severe."
Lombardy's pediatric emergencies, Italy, are overwhelmed by children with respiratory infections.
milano.corriere.it/notizie/cronac…

"Our structure is under duress. We have an average of 90 daily admissions at our emergency"
—Giuseppe Bertolozzi, Director of Emergency at the De Marchi hospital (Policlinico). Milan and other Lombardy cities are experiencing a severe wave of respiratory diseases in little kids

The Buzzi hospital, Milan, had 144 requests for help in the last 24 hours, 46 of which were for a yellow code, i.e. for "moderately severe cases—this puts a lot of pressure on us, we can't do our best"
—Gian Vincenzo Zuccotti, Director of Emergency and Pediatrics at Buzzi

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Dr Elisa Perego

@elisaperego78

Dec 1

Yes. We knew covid was a disaster in the making, and cardiovascular—clotting "bomb" in 2020 and 2021 already— in addition to all additional downstream effects of infection, like organ injury. Wasn't it a mistake and a deranged strategy to let SARS-CoV-2 rip? I say yes

"A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential consequences on the cardiovascular health of millions of people who survive infection worldwide."

#LongCovid

—2021

ahajournals.org/doi/10.1161/CI…

"we would like to emphasise the risk of associated stroke." [to covid]

"a 7·6-fold increase in the odds of stroke with COVID-19 compared with influenza was recently reported"

"endotheliitis or endotheliopathy [potentially leading to] thrombosis"

—2020

thelancet.com/article/S1474-…

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Dr Elisa Perego

@elisaperego78

Dec 1

If you see tweets by prominent people saying they tested positive, their covid is mild, and they're working from home, please consider: elite people have access to "tools" like top care many of us don't have. Also, covid can get worse with time: one reason why we say #LongCovid

Elite people and the very rich will have a very different covid experience than me, and you, and marginalised communities. They have fast access to antivirals and other early interventions. They have sick pay, or they're so rich they can just afford not working and rest

They have, most likely, their own home in affluent neighbourhoods, so they can modulate their risk for, and avoid, early reinfection, if they want to. They have optimal access to medical care.

Read 7 tweets

Dr Elisa Perego

@elisaperego78

Nov 28

@TheLancet

"In the past month we found a 30-fold increased incidence of Kawasaki-like disease. A similar outbreak of [severe] Kawasaki-like disease is expected in countries involved in the SARS-CoV-2 epidemic"

—13 May 2020—data from Bergamo—Italy @TheLancet

#MISC

thelancet.com/journals/lance…

@TheLancet

Some early pandemic history. This in the top @TheLancet journal from May 2020 is a first description of the severe, sometimes fatal multi-inflammatory syndrome seen in children weeks after SARS-CoV-2 infection — later known as MISC or PIMS.

"Children diagnosed after the SARS-CoV-2 epidemic began showed evidence of immune response to the virus, were older, had a higher rate of cardiac involvement, and features of MAS. The SARS-CoV-2 epidemic was associated with high incidence of a severe form of Kawasaki disease."

Read 12 tweets

Dr Elisa Perego

@elisaperego78

Nov 28

I will have to repeat this again. We knew covid and #LongCovid had a strong cardiovascular and endothelial component in 2020 and 2021 already. A lot of work on proving this, and raising the alert, was done by patients and advocates. It's published and recorded on many platforms.

Medical professionals and health bodies trying to gloss over this, and to suggest we've just discovered #LongCovid and covid have a severe cardiovascular impact: please do better. Letting SARS-CoV-2 rip was a severe error. Letting millions with no care was a severe error.

There was also emerging, very strong evidence published already in early 2020 about the pathophysiology of covid. This research clearly showed the devastating impact of the disease across the human body. Covid is not a "cold." Never was. Never been.

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