Two oral abstracts on the #STELLAR study (Sickle Cell Transplant Evaluation of Long-term and Late Effects Registry) presented by Dr. Sobenna George (hi!) and Dr. Lillian Meacham #ASH22 1/n
What's the problem? You can get DOR = diminished ovarian reserve or POI = primary ovarian insufficiency (early menopause). This is SUCH a good explanation!! #ASH22 2/n 
Small numbers but such great data, 30 females and 18 males, about 4-6 years post therapy (myeloablative transplants (mostly matched sib) and one each with gene tx) #ASH22 3/n
Of the 7 evaluable female patients here, 2 had normal AMH and the 5 who didn't, didn't have very high FSH so even though in DOR, could be considered for post-SCT fertility preservation! #ASH22 Great data, and more studies needed! 4/n
What about perceived risk of infertility and PROMIS sexual function and satisfaction survey results in this cohort (by Dr. Meacham) #ASH22 5/n
This cohort had the benefit of a control group. The pts who thought they had been told about a risk of infertility is still lower than I would imagine, 63% in females, 39% in males. Sexual function and satisfaction were in the normal range, but stat higher in males. #ASH22 6/n
Here are these conclusions. We now must take this information and continue to follow this - especially since this will be a long term consequence of transplant. #ASH22 7/7
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