Daniel Gewolb, MD Profile picture
Dec 24, 2022 4 tweets 3 min read Read on X
45F presents with painless progressive left eye vision loss. MR shows homogenous enhancement encasing the left optic nerve with an associated lesion at the entrance of the optic canal (yellow arrow)
#radres #futureradres #NeuroRad #MedTwitter @AlbanyMedRadRes ImageImageImage
Differential Diagnosis:

Optic Neuritis
Optic nerve sheath meningioma
Optic nerve glioma
Orbital sarcoidosis
Orbital lymphoma
Orbital pseudotumor

#Ophthalmology #radtwitter
Diagnosis: Optic nerve sheath meningioma

Remember the optic nerve is an extension of the CNS and therefore, is surrounded by meninges and arachnoid cap cells from which meningiomas arise. Look for the “tram-track” sign of enhancement surrounding the optic nerve
#Ophthalmology
Optic neuritis would be painFUL and display enhancement of the nerve itself and perineural fat

Optic nerve gliomas create enlargement of the nerve with variable enhancement typically in NF-1 patients

Other diagnoses are variable though typically present as intraorbital masses

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More from @daniel_gewolb

Dec 10
Back from Belize! 🇧🇿

🔷What is the most likely diagnosis in this 25 y/o F w/ a band-like scalp lesion and local alopecia?

#Medicine #radres #futureradres #ENT #Rheum #Neurology #neurosurgery #Ophthalmology #FOAMed Image
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Answer: Linear Scleroderma aka Scleroderma en coup de sabre

🔷Linear scleroderma is a focal form of scleroderma resulting in atrophy and alopecia of the frontal or frontoparietal scalp

🔷Atrophy involves the subjacent skull +/- underlying brain parenchyma (as seen in this case)
🔷Brain parenchymal abnormalities may have calcifications or micro-hemorrhage

🔷Linear scleroderma is associated w/ progressive facial hemiatrophy (Parry-Romberg syndrome) Image
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Read 4 tweets
Nov 27
⭐️ What is the most likely diagnosis in this asymptomatic patient? What would your recommendation be if any?

#ENT @ASHNRSociety #Medicine #radres #futureradres #Neurology #Neurosurgery #ophthalmology #FOAMed Image
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Answer: Benign-appearing notochordal lesion (formally ecchordosis physaliphora, EP)

💡 If no remote priors for comparison, recommend 6 month follow up which can be extended if unchanged at that time
🔷Pathologic nomenclature was revised from EP to benign notochordal cell tumor (BNCT)

🔷Notochordal remnants are a pathologic spectrum ranging from benign (EP/BNCT), indolent, intermediate, & aggressive chordomas
Read 7 tweets
Nov 24
⭐️What is the most likely diagnosis in this 40 y/o M presenting w/ 10 days of L neck/throat/ear pain, worsened by neck palpation and head turning?

🔷PMH: None
🔷ESR/CRP: Mildly ⬆️

#Medicine #Neurology #neurosurgery #ENT #radres #futureradres #FOAMed @ASHNRSociety Image
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⭐️ Answer: Transient Perivascular Inflammation of the Carotid Artery (Carotidynia or Fay syndrome)
🔷Pathology: Unknown inflammatory process of the carotid wall

🔷Epidemiology:
▶️Young and middle age adults
▶️No gender predilection
Read 7 tweets
Nov 22
What is the most likely diagnosis in this 30 y/o M presenting with seizures, fever & headache?

🔷CSF x2:
Worsening neutrophilic pleocytosis despite Abx
Negative infectious studies
No malignancy on cyto/flow
OCBs +

🔷CT CAP: normal
#neurology #medicine #radres @AlbanyMedRadRes Image
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Additional image 👇
#futureradres #Neurosurgery #FOAMed Image
Answer: FUEL “FLAIR-variable unilateral enhancement of the leptomeninges” in MOGAD

🔷MOG antibody-associated disease (MOG-AAD)

Path: MOG-AAD is an autoimmune inflammatory demyelinating disease targeting oligodendrocytes
Read 12 tweets
Nov 19
⭐️ Classic case: 45 y/o Female presents w/ intermittent R pulsatile tinnitus for 1-2 years, what’s the most likely diagnosis?

#meded #medicine #ENT #Neurology #radres #futureradres #neurosurgery @ASHNRSociety Image
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Answer: Glomus Tympanicum Paraganglioma

🔷PATHOLOGY: Benign tumor arising from glomus bodies along the inferior tympanic nerve (Jacobson nerve)
🔷CLINICAL:
▶️Vascular retrotympanic mass
▶️Pulsatile tinnitus
▶️Female predominance (~3:1)
▶️Generally middle age at diagnosis
Read 8 tweets
Nov 15
60 y/o F presents w/ several months of confusion, word finding difficulty & gait dysfunction

🔷What is your best guess and differential?

🔷More images in 🧵
#MedEd #radiology #Neurology #radres #neurosurgery #medicine #ENT #Ophthalmology #futureradres Image
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🔷More images 👇 Image
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Answer: Glioblastoma on pathology

🔷Imaging: Tumor, high grade glioma vs lymphoma

🔷This case of glioblastoma is not classic and has overlapping features with lymphoma
Read 11 tweets

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