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Jan 9 • 19 tweets • 12 min read
1. Shall I continue the #SIDU format in 2023?

"Syndemic infectious disease update 230109, incl. politics of #sars #mpox #climate"

We learned the wrong lessons from pandemic errors in China and the west but I can't fill holes in public policy. Some of you/us need to learn fast.
2. Here another outstanding thread by @RealCheckMarker that's sure to fly under the radar.
@RealCheckMarker 3. As shared previously. Hundreds of millions will suffer from Long SARS. We not only waste the ongoing population-level experiment - because states don't collect data, despite their legal obligations under IHR 2005 - but even threw away data that existed.
@RealCheckMarker 4. You need to be no prophet to see where this ends. Nothing against prophets, but we need them for higher-order questions. Having basic high-school literacy suffices.
@RealCheckMarker 5. As the old saying goes, profit generates false prophets; real prophets profit no one 😂
@RealCheckMarker 6. Prophet of the year award 2021/2022 went to the documentary #DontLookUp, here Ariana Grande closing with the line "Just look up - Listen to the goddamn qualified scientists."

Who deserves / got the award this year?
@RealCheckMarker 千萬別抬頭-電影主題曲 Ariana Grande just look up
7. As #DontLookUp shows, media keep the bad news light. Society solves modern governance challenges only if people are well informed.

There's a remarkable aesthetic quality to Antarctica's disintegration: please learn the details, so we all have a chance. earth.nullschool.net/#current/ocean…
8. Impressive, we can watch the disintegration of #B22a live, exposing Thwaites.

Behavioral change will be orders of magnitude harder than shooting a man or satellite into outer space.

Can we get people to be kind to each other? That would truly impress.
9. Earlier today, several epidemiologist accounts were shadow-banned temporarily. Someone must have protested twitter's eight-headed content moderation board because it promptly reversed the decision. I credit @NeoliberalSnow, mildly well done John!
@NeoliberalSnow 10. Antarctica disintegration live: you can see B22a from space. Follow the breaking news; shame if I were alive at this pivotal moment in Earth history but not watching and educating the public about it! - Leon, one of the gifted communicators, bedankt! worldview.earthdata.nasa.gov/?v=-5600379.86…
One of the must-follow accounts for climate scicomm: @LeonSimons8
11. What will society look and feel like in 2035?

(a) With strong SARS policy enacted, for eradication / mitigation in 2023-2025, (b) and without?

Great video, appreciated @amandalhu
@amandalhu Fantastic overview why policy matters. You can easily tell the state of SARS (and climate) discourse by how weakly and ineffectively this is argued by most.

Thanks @BernieDogs4, this blew my mind mostly because people used to smoke on planes? Savages! 😂

preventioninstitute.org/publications/f…
My monthly reminder that "Living with COVID" may for many well mean living childless or shorter than intended. Best wishes for the people who "moved on".
12. Resharing this lovely account for writers or workers of the mind by Margaret Atwood.
13. Japan starting to catch up with Taiwan.
All this well above my nonexistent pay class - you may want to devote real resources if you want to solve this.

We - on twitter - keep warning that it's urgent, but we've been doing saying so for three years already sans results. Offline politics seems to lag reality. Good luck.
14. How can we end the SARS pandemic?

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More from @_ppmv

Paul Maidowski Profile picture
Jan 11
1. "Live with COVID," we were told. How long exactly?

We have 4,100 HIV infections, and more than 600,000 SARS infections per day (1.5 million/year v. 660 million/1100 days).

Both cause chronic immune activation, a systemic pro-inflammatory cytokine milieu, and premature aging. ImageImage
2. Frailty - immunosenescence - follows. The effect is strongest in children. Literature on telomere shortening in HIV+ children exists.

This is what Drosten means, warning that at 30, unvaccinated SARS+ children may "have the immune system of an 80 yo."
journals.lww.com/aidsonline/ful…
3. He errs when he implies or claims vaccines will protect children. Their effect on LongCOVID (=chronic immune activation) is numerically irrelevant.

All this is already leaving out the finer reasons that make SARS-CoV-2 dangerous - positive feedback effects and other concerns.
Read 14 tweets
Paul Maidowski Profile picture
Jan 10
When I designed these pages (indeed half a book LOL), I did not expect how timely they'd be within less than five years. Image
Observers of system dynamics to the fore please; we badly need those systems thinking skills in positions of power (or at least public visibility, IF ONLY anonymous and on twitter)
Read 9 tweets
Paul Maidowski Profile picture
Jan 10
1. What do Hotez' MERS-/SARS-CoV/-2 vaccines tell us?

(1) He works on patent-free vaccines (Corbevax) - good. I don't think he engineered SARS-CoV-2.

(2) If experts categorically deny the possibility of a human origin, don't trust them; they are in denial and they know it. 🫠🤷‍♂️
en.wikipedia.org/wiki/Corbevax
en.wikipedia.org/wiki/COVAX
Funny. Let's call @PeterHotez out for this. You think after tens of millions dead from SARS-CoV-2, multiples to come, there should be no investigation? It is a criminal justice matter, I doubt virologists' circling the wagon can stop the course of justice.
Read 4 tweets
Paul Maidowski Profile picture
Jan 10
I keep thinking about this, but just can't make sense of it. A 53% drop in sperm counts, 3 months after SARS infection, must concern women as well as men. - Are people planning on living their best childless lives? Other than for true Menscheinfeinde, this is terrible news.
How I stopped worrying about climate and started reading immunology textbooks. Image
* Menschenfeinde. As kali says, we've been tweeting about it for years, no one wanted to listen. VERY strange to see it happen live.
Read 7 tweets
Paul Maidowski Profile picture
Jan 9
On climate and SARS, I don't think reduced visibility helps anyone right now; will leave my account unlocked for now. So the band plays on,
And the dolphins jump into the sun.
If everyone can catch up with Dr. Hansen's latest preprint and ask policymakers what they intend to do about that - and about not all of us catching SARS all the time -, both might help.
Read 5 tweets
Paul Maidowski Profile picture
Jan 9
I mentioned SARS/MERS-CoV (1) persist in the renal epithelium in 1 in 3 patients until cells regenerate after 500-787 days; (2) are airborne; (3) draw down rather than build immunity; (4) infections drive mutations and should stop; (5) HIV medicine may help patients access care.
None of this new (to attentive readers) or even controversial. Yet it attracted an outsize crowd of fools and personal insults by at least one researcher, so I deleted the post. I gain nothing from useless controversy, it's just distraction. Good luck out there,
Did media and policymakers reconcile the contradiction yet that they believe Drosten just told them "the pandemic is over" in the same interview in which he told them in a deadpan way that unvaccinated children at 30 may have the immune system of an 80 yo.
Read 5 tweets

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