Sarah Hughes Profile picture
Jan 10, 2023 29 tweets 14 min read Read on X
December 2022 round up of #PANS #PANDAS - relevant or related peer-reviewed papers and media articles that may be of interest. Complied with @np9000. We hope you find it useful. (1/29)

@PandasPans @theEXPANDAssoc @BPNA_org @ASPIREpans @PANDASPPN @CAMHSNetwork @NeuroimmuneFDN ImageImage
Prevalence of pediatric acute-onset neuropsychiatric syndrome (PANS) in children and adolescents with eating disorders. Aman, M. et al. J Eat Disord 10, 194. 2022. jeatdisord.biomedcentral.com/articles/10.11…
(2/29)
Group Psychotherapy for Parents of Youth with Pediatric Acute-Onset Neuropsychiatric Syndrome. Ellerkamp, H. et al. J Clin Psychol Med Settings. 2022. link.springer.com/article/10.100…
(3/29)
An unusual case of PANDAS – diagnostic evaluation, treatment, & the remarkable outcome. Divya Raj, T.G. et al. Archives of Disease in Childhood. 2022. 107:A224-A225 [Abstract 589]. adc.bmj.com/content/archdi…
(4/29)
Autoantibody-associated psychiatric syndromes: a systematic literature review resulting in 145 cases. Endres, D. et al. Psychol Med. 2022 Apr;52(6):1135-1146. cambridge.org/core/journals/…
(5/29)
Editorial: Environmental risk factors and inflammation in psychiatric and neurological disease. Meier, U.-C., S. Ramagopalan, & N. Müller, Frontiers in Psychiatry, 2022. 13. frontiersin.org/articles/10.33…
(6/29)
Peripheral blood cellular immunophenotype in depression: a systematic review and meta-analysis. Foley, É.M. et al. Mol Psychiatry. 2022. nature.com/articles/s4138…
(7/29)
Can group A streptococcus infections be influenced by viruses in the respiratory tract? Turner, C.E. The Lancet: Infectious Diseases. 2022. thelancet.com/journals/lanin…
(8/29)
Schizophrenia: The new etiological synthesis. Rantala, M. J. et al. Neuroscience & Biobehavioral Reviews, Vol. 142. 2022. 104894 doi.org/10.1016/j.neub…
(9/29)
Rituximab as an adjunctive treatment for schizophrenia spectrum disorder or OCD: 2 open-label pilot studies on treatment-resistant patients. Bejerot, S. et al. Journal of Psychiatric Research, 2022. In Press, Journal Pre-proof. sciencedirect.com/science/articl…
(10/29) @Doc_Cunningham
Evidence of innate immune dysfunction in first-episode psychosis patients with accompanying mood disorder. Hughes, H.K. et al. J Neuroinflammation 19, 287 (2022). doi.org/10.1186/s12974…
(11/29)
Novel anti-cytoplasmic antibodies in cerebrospinal fluid and serum of patients with chronic severe mental disorders. Endres, D., et al., World J Biol Psychiatry, 2022. 23(10): p. 794-801. tandfonline.com/doi/full/10.10…
(12/29)
A weighted blanket increases pre-sleep salivary concentrations of melatonin in young, healthy adults. Meth, E.M.S. et al. J Sleep Res. 2022 Oct 3:e13743 [Epub ahead of print]. doi.org/10.1111/jsr.13…
(13/29)
Dysregulation of complement system in neuropsychiatric disorders: A mini review. Perez Sierra, D. et al. Biomarkers in Neuropsychiatry, Vol. 7, 2022, 100056. doi.org/10.1016/j.bion…
(14/29)
Neuroimmune mechanisms in fear and panic pathophysiology. McMurray & Sah. Frontiers in Psychiatry, 2022. 13. frontiersin.org/articles/10.33…
(15/29)
An integrated cytokine and kynurenine network as the basis of neuroimmune communication. Stone, T.W., et al., Frontiers in Neuroscience, 2022. 16. frontiersin.org/articles/10.33…
(16/29)
Editorial: Novel pharmacological treatments in sleep disorders. De Luca, Todd, and Burgess. Frontiers in Neuroscience, 2022. 16. frontiersin.org/articles/10.33…
(17/29)
Impact of pre-existing chronic viral infection and reactivation on the development of long COVID. Peluso, M.J., et al., The Journal of Clinical Investigation, 2022. jci.org/articles/view/…
(18/29) @LongCOVIDemail @LongCovidKids
Psychotropic Medication Use and Psychiatric Disorders During the COVID-19 Pandemic Among Danish Children, Adolescents, and Young Adults. Bliddal, M., et al., JAMA Psychiatry, 2022.
jamanetwork.com/journals/jamap…
(19/29)
Innate immune dysfunction and neuroinflammation in autism spectrum disorder (ASD). Hughes, H.K., R.J.Moreno, & P. Ashwood, Brain, Behavior, and Immunity, 2022. sciencedirect.com/science/articl…
(20/29)
Case report: Advice for schools on managing functional tic-like behaviours. Owen, T., et al., Frontiers in Psychiatry, 2022. 13. frontiersin.org/articles/10.33…
(21/29)
UKHSA update on scarlet fever and invasive group A strep. UK Health Security Agency. Last updated 29 December 2022. gov.uk/government/new…
(22/29)
Research and analysis: Group A streptococcal Infections: first update on seasonal activity in England 2022-2023. UK Health Security Agency. Last updated December 2022. gov.uk/government/pub…
(23/29)
Group A streptococcus interim clinical guidance. UKHSA, NICE, RPS, RCPCH, RCGP, NHS England. Last updated 30 December 2022. england.nhs.uk/wp-content/upl…
(24/29)
Anti-interneuron antibodies in rapid-onset pediatric OCD: clinical generalization and target identification. Project Leader: Pittenger, C.
pandasnetwork.org/nimh-awards-ya…
@PANDASnetwork @PandasPans @BPNA_org @CAMHSNetwork @theEXPANDAssoc
(25/29)
Mum's six year nightmare after son caught Strep and was left unable to walk. Neil Shaw. 16 Dec 2022. Devon Live. devonlive.com/news/uk-world-…
(26/29) @DevonLiveNews @PandasPans
Long-Term Consumption of Food Allergens May Lead To Behavior and Mood Changes. Kumi Nagamoto-Combs. 11 Dec 2022. Neuroscience News [Source: The Conversation] neurosciencenews.com/food-allergens…
(27/29) @NeuroscienceNew
I’m a Neurologist, hear me roar. Ruhoy, I.S. Dec 2022. MedPage Today. 6 medpagetoday.com/opinion/second…
(28/29) @MedPageTodayCME
The misdiagnosis that sent me to psychiatric hospital. Ewa Headley, 20 Dec 2022. BBC. bbc.co.uk/ideas/videos/t…
(29/29) @BBCRadio4

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More from @SHughesDr

Feb 15, 2023
This case report is of interest for a number of reasons…..Case report: Varicella associated neuropsychiatric syndrome (VANS) in ... sciencedirect.com/science/articl… 1/n @PandasPans @ASPIREpans @PANDASPPN
A) the children present with a #PANS (paediatric autoimmune neuropsychiatric syndrome) presentation. But the authors have created yet another new term “VANS”, presumably to avoid the controversies surrounding PANS 2/n
B) the subacute/acute onset of 3-6 weeks. Many parents are told their child can’t have PANS because onset took longer than 3 days - which has become the default definition of “acute onset”. Note that endres et al 2022 defined acute onset as <3 months 3/n
Read 9 tweets
Oct 9, 2022
Here is the round-up of #PANS #PANDAS and related publications and media articles released in September 2022. Collated by myself and @np9000.
@PandasPans @ASPIREpans @theEXPANDAssoc @NeuroimmuneFDN
#PansPandasAwarenessDay
🧵1/17
Pediatric Autoimmune Neuropsychiatric Disorders Associated with Group a Streptococci: Etiopathology and Diagnostic Challenges. Hutanu, A., et al. Cureus 14, no. 8 (Aug 2022): e27729. pubmed.ncbi.nlm.nih.gov/36106298/
(2/17)
Back to the Future: The Role of Infections in Psychopathology. Focus on OCD. Della Vecchia, A. & Marazziti, D. Clin Neuropsychiatry. 2022 Aug;19(4):248-263. doi.org/10.36131/cnfio…
(3/17)
Read 17 tweets
Oct 9, 2022
Across the world, today is #PANS #PANDAS awareness day. My son developed #PANS in December 2018. I will never forget the day and time it first presented itself. I did not know at that time how his and his family's lives would be irrevocably changed 🧵
Right now, my son is doing well. This is because of the help I found via the support network gathered around the UK #PANS #PANDAS charity, PANS PANDAS UK @PandasPans
#PANS #PANDAS are conditions with relatively "simple" treatment approaches. Appropriate & timely treatment is stopped by a lack of knowledge by the clinical population & by a small but influential population of clinicians who decline to treat them. Fig Swedo 2017
Read 22 tweets
Jun 4, 2022
Been experimenting with a brief monthly round-up of publications (peer-reviewed & media articles) that may be interest #PANS #PANDAS community. Small scale stuff, but there may be scope to turn this into a mail list so all the links would conveniently arrive in your inbox 1/n
March's round-up illustrated in the two jpegs above. Thank you @np9000 for being my wingman!
OCD in Pans/Pandas in Children: In Search of a Qualified Treatment; a Systematic Review & Metanalysis. Cocuzza, et al. Children 9, no. 2 (2022). dx.doi.org/10.3390/childr…
#PANS #PANDAS 2/n
There follows:
Neuroinflammation in a Rat Model of Tourette Syndrome. Zhongling, Ke, Chen Yanhui, Chen Guofeng, and Liu Yanyan. Original Research, Frontiers in Behavioral Neuroscience 16 (2022). doi.org/10.3389/fnbeh.…
3/n
Read 17 tweets
May 7, 2022
The British Association of Social Workers have published Fabricated & Induced Illness & Perplexing Presentations Practice Guide basw.co.uk/resources/fabr…
(PP ~ MUS) 🧵1/20
@doctorasadkhan @NurseDiane2020 @PandasPans @LongCovidKids @FiGullonScott @BASW_UK
This well-considered & positive document provides guidance to social workers (SW) to enable them to adopt professional curiosity & respond ethically to FII concerns. The following points are some that I feel are relevant to #PANS #PANDAS #LongCovid #MECFS #EDS communities 2/20
lt is recommended SW need to be aware of the lack of evidence for currently used indicators for FII & perplexing presentations and the high incidence of these indicators identifying children where illness is neither fabricated or induced #PANS #PANDAS #MECFS #EDS #LongCovid 3/20
Read 20 tweets

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