Thread by @Jikkyleaks

WHOA... this looks like #surgisphere the sequel

The claim that statins improve the outcome of #COVID was proven fake when the original authors made it.

Now you miraculously found another database?

No way.
@Inspiteofmysel1 @chrismartenson

This is the ASA abstract.

If this data is published without the data set for analysis it should be immediately stamped with an expression of concern

asahq.org/about-asa/news…

There are red flags all over this. This is EXACTLY what #surgisphere claimed.

"The Institutional review boards said this was exempt"

It doesn't work like that.
Where is the IRB reference?

You can't just give up 90,000 patients' personal data without ethics approval.

This is from the same database published by the same author.

No indication of where the data was from.

ncbi.nlm.nih.gov/pmc/articles/P…

All these people put their affiliations as the Dept of Surgery but Ettore Crimi is supposed to be affiliated with the department of anesthesiology

And a handful of surgeons trawling through a 93,000 patient database?

Possible, but unlikely without help.

For comparison, remember this infamous 44,000 patient study that had the billion-dollar resources of every Pfizer scientist thrown at it, and a long list of authors (who didn't actually write the paper).

The documents required to sift through double that number of patients is phenomenal.

Remember that the FDA needed 75 years to check their documents from the 44,000 Pfizer trial?

But they crunched the data with a handful of helpers?

euroweeklynews.com/2021/12/09/fda…

Lead author Ettore Crimi is affiliated with @EnvisionLeads a large healthcare provider in the US..

Did they release their patient's data without IRB approval?

They sure like propaganda

https://twitter.com/EnvisionLeads/status/1367143881033318402

And, just like #surgisphere's Sapan Desai - whose fraudulent papers were ghost written - Crimi had a quite sparse publication history prior to 2020.

Small studies and case reports. Typical for a clinician.
pubmed.ncbi.nlm.nih.gov/?term=%28%28cr…

Yet we're expected to believe that someone handed Crimi a 93,000 patient database without IRB approval for analysis and they miraculously found that statins reduce COVID death rates, 3 years after the data was collected?

Not buying it. Sorry

And who reported this?

Emily Henderson of "News Medical Life Sciences" @newsmedical, a pharma marketing journal part of the AZO marketing network.

So you can take the claim with a pinch of salt.

Maybe I'm wrong here - but I will make this prediction:

Ettore Crimi will never release that dataset for analysis.

You know why?

Half of their ventilated patients died.
HALF.

And that database - if it's real - will show what treatment those patients did or didn't receive that set them on a pathway to a 50% mortality

@richardursomd @P_McCulloughMD @LynnFynn3

And I will hazard a bet that the patients in this study did not get the #3tablets of antibiotics that would have prevented them going to a ventilator with a 50% mortality.

https://twitter.com/TheJikky/status/1604543666135367680

Just before Crimi's recruitment to the "COVID publication lottery prizes" he published a paper on antibiotic resistance - the same dogma we saw in the #3tablets scandal.

ncbi.nlm.nih.gov/pmc/articles/P…

So as an AMR (antimicrobial resistance) steward it's a good bet that their patients didn't get antibiotics to prevent secondary pneumonia in COVID. Hence the 50% mortality. Good for recruitment to a study though, I guess.

Yet there is something fishy about that clinical epigenetics paper - because Crimi has NO published prior background in epigenetics. It's not something you just write about. It's one of the most complex fields of molecular biology.

He's an anaesthetist.
@JesslovesMJK

@JesslovesMJK His first epigenetics paper was in 2019 with the same group of people - from Italy, not the US.

@JesslovesMJK And coincidentally the work was funded out of Italy with this grant number that just happens to be associated with Dr Concetta Schiano

@JesslovesMJK Who also happens to have published on epigenetics in a completely different journal at the same time without Crimi.

And happens to have a PhD and a history of publications in epigenetics
pubmed.ncbi.nlm.nih.gov/?term=schiano%…

And coincidentally Schiano - the PhD epigeneticist - has a very similar writing style to Crimi - the anaesthetist.

These two passages are from different papers. The first, Schiano's (pubmed.ncbi.nlm.nih.gov/32790754/) and the second Crimi's (ncbi.nlm.nih.gov/pmc/articles/P…)

So the explanations for this might be that Crimi is Schiano's PhD student and he is doing a 3-year+ sabbatical in the lab.

Or that Schiano ghost wrote the epigenetics papers.

If it's the latter then Ettore Crimi has some explaining to do

Because otherwise it's just another #surgisphere scandal used to push pharma drugs under the umbrella of "COVID".

And given that I was right about the first one, I would put a few dollars on the answer to this one.

/end
the-scientist.com/features/the-s…

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