The struggling brain is already trying to shift to ketones for fuel. (1/4)
"The bioenergetic system of the brain is compromised early in the progression of AD and is evident during the prodromal (preclinical) stage of the disease. (2/4)
Glucose hypometabolism and a compensatory shift to an alternative fuel substrate, ketone bodies, have been established as a metabolic phenotype characteristic of the AD brain in both clinical and preclinical studies." (3/4) doi.org/10.1016/j.ebio…
Let me be clear. I have zero interest in using my precious energy, arguing with skeptics. I think this is where we lose momentum and power in this movement to bring this treatment to people. (1/5)
Any skeptic worth their salt, I would hope, understands how to evaluate levels of evidence and can find Google Scholar. Don't waste your precious life force arguing with people who are not interested in truly learning. (2/5)
Please do not allow them to waste your time and energy. Some are using it to shore up their own views to maintain their comfort of current beliefs about what is possible. And that is a disingenuous use of your time and attention. (3/5)
Some people think ketogenic diets are restrictive and that any kind of restriction is bad. But I think we need a short thread defining what food is and is not. 🧵(1/11)
A lot of you are calling highly processed products "food". They are not food. They deplete more nutrients than they provide. They are drugs. They are designed to hijack your neurochemistry and make you crave them and buy them more. (2/11)
Just because there is a commercial industry that wants to make money off of messing with your brain, and they infer it's food, doesn't mean it is. (3/11)
It is an evidence-based and strategic nutritional intervention to rescue mood, cognitive functioning, and basically all-around metabolic function. (2/6)
Some people will need to restrict carbohydrates to treat chronic illnesses of the brain and the body. And they don't need misinformed mental health counselors scaring them and telling them they are going to develop an eating disorder. (3/6)
Reduction in cerebral metabolic rate of glucose utilization, particularly in the entorhinal cortex and hippocampus, correlate with cognitive deficits over time. 🧵 (1/4)
This reduction in glucose utilization most accurately predicts future cognitive decline in normal individuals as well as conversion to mild cognitive impairment. (2/4) doi.org/10.1016/j.ebio…
Stop minimizing that you can't find your keys, or your words, or remember what you walked into a room to look for. It's not normal aging. It's not material for funny memes. Stop laughing about it with your friends. Because it's really not funny. (3/4)
So you're talking to your doc about the use of a ketogenic diet to treat your mental illness, and they basically tell you that they are dangerous. What to do? 🧵(1/10)
Some physicians are misinformed and believe there are concerns over cardiovascular risk, decreased bone health, and strain on the kidneys. (2/10)
However, there is no good evidence to support these claims. In fact, some studies suggest the opposite. Once again, I am sorry for the inconvenience, but you are going to have to educate them and self-advocate. (3/10)
Did your doctor refer to the #ketogenic diet as a fad? Well, I'm sorry. But you're going to have to take a moment to educate them. 🤷♀️It's time for a thread. 🧵(1/7)
A common concern is that the ketogenic diet is just a fad weight loss diet & won't help with mental illness. This is far from the truth. (2/7)
The ketogenic diet has been used as a medical intervention for over 100 years to treat seizures in children with epilepsy. It's also used for adults with epilepsy. (3/7)