You may not know who Dr. Carlo Longhiano is, but you will after this thread. I met him at the Metabolic Psychiatry Retreat put on by @janellison and @metabolic_mind this year! 🧵(1/8) #metabolicpsychiatry
@janellison@Metabolic_Mind Dr. Carlo Longhitano is the Associate Professor of Psychiatry at James Cook University (Australia) and a psychiatrist at North Queensland Forensic MH Services. (2/8)
@janellison@Metabolic_Mind He obtained his MD in 1999 (Italy) before completing his psychiatric residency in Oxford and London (United Kingdom). (3/8)
@janellison@Metabolic_Mind Carlo has held senior positions in forensic psychiatry across London and Australia. Since 2019, he has collaborated with Professor Sarnyai, leading to a PhD project on the effects of nutritional interventions in psychosis. (4/8)
@janellison@Metabolic_Mind Carlo is the co-investigator at JCU's randomized clinical trial of ketogenic diet vs. standard diet in adults with bipolar disorder and schizophrenia. The project is supported and funded by the Baszucki Brain Research Fund. (5/8)
@janellison@Metabolic_Mind Additionally, Carlo is a member of the forensic faculty of the RANZCP and an Early Career committee member of the International Society for Nutritional Psychiatry Research. He is the author of several peer-reviewed articles and two textbook chapters. (6/8)
@janellison@Metabolic_Mind He told me during the retreat that he sends people to my blog to educate them about ketogenic diets for mental illness and neurological disorders. He liked that it was geared toward the general public for understanding! So that was amazing! (7/8)
Why do we need seniors to have access to a ketogenic diet to help ward off dementia? Because telling them to eat more fish and blueberries is woefully insufficient! Think I am making this up? I am not. It's time for a thread on a recent study. 🧵 (1/19)
The objective of this study was to examine the relationship between consumption frequency of meat, fish, fruits, and vegetables and long-term risk of dementia and Alzheimer’s disease while taking into account the possibility of protopathic bias (i.e., reverse causation). (2/19)
The researchers analyzed data from the Three-city study, which followed 5,934 volunteers aged 65 and over for 12 years. (3/19)
We need to talk about the role of GABA in mental illness and neurological disorders. And then I am going to explain to you why ketones can help regulate this neurotransmitter. 🧵 (1/21)
GABA (gamma-aminobutyric acid) is the main inhibitory neurotransmitter in the brain, and it plays a critical role in regulating neuronal excitability and maintaining the balance between neuronal excitation and inhibition. (2/21)
GABAergic dysfunction has been implicated in a wide range of psychiatric and neurological disorders, including #anxiety disorders, #depression, #epilepsy, #schizophrenia, and #autism spectrum disorders. (3/21)
Dr. Eric Kossoff was an excellent addition to the Metabolic Psychiatry Retreat put on by @janellison and @metabolic_mind this year! Let me tell you why this was helpful in paving the way towards #metabolicpsychiatry 🧵(1/8)
@janellison@Metabolic_Mind Dr. Eric Kossoff is a Professor of Neurology and Pediatrics at Johns Hopkins University in Baltimore, Maryland. (2/8)
@janellison@Metabolic_Mind He is a pediatric epilepsy specialist and is currently the Medical Director of the Pediatric Ketogenic Diet Center at Johns Hopkins. (3/8)
I want you to know that the ketone body Acetoacetate is a powerful gene-signaling molecule. (1/14)
Acetoacetate has been shown to inhibit histone deacetylase (HDAC) activity in the brain, leading to increased histone acetylation and altered gene expression. (2/14)
Acetoacetate has been shown to inhibit HDAC activity, leading to increased histone acetylation and altered gene expression. This affects the expression of genes involved in synaptic plasticity and cognitive function in the brain. (3/14)
Did you know that Dr. Elena Gross was at this years' Metabolic Psychiatry Retreat hosted by @janellison and @metabolic_mind? I want you to know about some of the people bringing #metabolicpsychiatry to the masses through their work! So it's time to learn about Elena! 🧵(1/7)
@janellison@Metabolic_Mind Dr. Elena Gross has a BSc in Psychology (University of York), an MSc in Neuroscience (University of Oxford), and PhD in Clinical Research (University of Basel). She is the founder and CEO/CSO of KetoSwiss AG. (2/7)
@janellison@Metabolic_Mind Elena used to be a chronic migraine patient, and due to the lack of tolerable and efficacious treatment options, she pursued an MSc in Neuroscience (University of Oxford), where she discovered the key role of metabolism in migraine. (3/7)
Would you like to read about a case report in which a ketogenic diet resolved lifelong asthma symptoms? 🧵(1/22)
The case study is about a 32-year-old man from Saudi Arabia who is an English teacher, married with two children, and has a history of obesity and bronchial asthma since childhood. (2/22)
Shortness of breath, cough, and audible wheezing chest were usual symptoms during his asthma exacerbations. His asthma triggers were seasons transitions, exercise, animals like horses, and some fruit like melons. (3/22)