Discover and read the best of Twitter Threads about #schizophrenia

Most recents (24)

Ron Davis: "25% #MECFS patients have MS."

GeNeuro: "25% of longhaulers have a reactivation of the HERV-W protein."

My logic:
In ME: EBV reactivates HERV-W, and this leads to MS.
In LC: Sars-Cov-2 leads to EBV reactivation, EBV reactivates HERV-W, resulting in MS.

Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis… Image
Read 6 tweets
#Schizophrenia is a chronic and severe mental disorder characterized by a range of symptoms, including hallucinations, delusions, disorganized thinking and speech, diminished emotional expression, and social withdrawal. Image
🧵 The onset of schizophrenia typically occurs in late adolescence or early adulthood, although it can affect individuals at any age.
🧵 Genetic factors play a significant role in the development of schizophrenia, with a higher risk observed in individuals who have close relatives with the disorder.
Read 12 tweets
تھانٹوفوبیا یعنی موت کا پیتھولوجیکل خوف
یہ نفسیاتی مرض اس وقت ٹرگر ہوتا ہےجب انسان کی "سماجی حیثیت" کو خطرہ لاحق ہو۔ایساشخص تخلیقی صلاحیت یا پروفیشنلی جب بحران کا شکار ہوتاہے تو وہ ایک ناقابلِ برداشت ذہنی کرب کا شکار ہوجاتا ہےجو کہ مرض کی صورت اختیار کرلیتا ہے
تھانٹوفوبیا کا شکار انسان 4 مختلف خوف کی پرتوں میں سےسب یا کسی ایک یا کچھ میں سسکتا ہے۔
1:بیماری یا معذوری کاخوف
2:تنہائی یا دیوالیہ ہوجانے کا ڈر
3:اپنوں کے کھو جانے کا خوف
4:"گناہوں" کے بدلے پکڑ کے خوف میں بری موت کا خیال

یوں مریض کے سوچنے اور شعور کی صلاحیت مفلوج ہوجاتی ہے
تھاٹوفوبیس دراصل زندگی کے کھوکھلے پن یا بےمعنویت کا شکار ہوتےہیں
عموماً ایسے لوگ موت (کےخوف) کو inevitable revenge کے ساتھ جوڑ لیتے ہیں۔
ایسے انسان جو دوسروں کی زندگیاں کنٹرول کرنےکی pathological خواہش میں مبتلا ہوں وہ موت کو کنٹرول نہ کرنےکی سوچ سے بھی ڈپریشن کا شکار ہوتےہیں
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We need to talk about the role of GABA in mental illness and neurological disorders. And then I am going to explain to you why ketones can help regulate this neurotransmitter. 🧵 (1/21)
GABA (gamma-aminobutyric acid) is the main inhibitory neurotransmitter in the brain, and it plays a critical role in regulating neuronal excitability and maintaining the balance between neuronal excitation and inhibition. (2/21)
GABAergic dysfunction has been implicated in a wide range of psychiatric and neurological disorders, including #anxiety disorders, #depression, #epilepsy, #schizophrenia, and #autism spectrum disorders. (3/21)
Read 22 tweets
Thread Alert! 🧵Starting the conversation with your doctor about using a #ketogenic diet to treat mental illness can be daunting, but it's important to be proactive about your health. #bipolar #depression #schizophrenia #ocd #anxiety (1/9)
Mention the information you've heard from other doctors and the specific mental health condition you are hoping to treat with the #keto diet. (2/9)
Express your eagerness to try the diet, but also emphasize your concern for safety and your willingness to work closely with your doctor. (3/9)
Read 9 tweets
Can eating a ketogenic diet improve symptoms of serious mental illness? Yes. Yes it can. And once again, I am not just making this up. 🧵(1/5)
A study was done at Clinique du Castelviel (Psychiatric Hospital) in Castelmarou, France, with 28 participants (12 #bipolar, 6 major #depression, and 10 #schizophrenia). (2/5)
They were put on classic keto macros. Do you want to know what happened in this severely mentally ill, hospitalized population? (3/5)
Read 5 tweets
Thread alert! Advice from @bschermd at @Metabolic_Mind about the #ketogenic diet as a treatment for #mentalillness 🧵⬇️ #depression #ADHD #Bipolar #Schizophrenia #OCD #Anxiety #PTSD (1/8)
@bschermd @Metabolic_Mind "Remember our caution. Therapeutic
nutritional #ketosis or simply starting
a ketogenic diet is a powerful #health
and medical intervention that can change
your body's #metabolism and could
dramatically alter (2/8)
@bschermd @Metabolic_Mind #brain function, medications, #sleep patterns, #energy levels, and other physiologic functions. You should not start a keto diet on your own. (3/8)
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"When we (@Metabolic_Mind) mention mental illness we're referring to severe
#depression #bipolar disorder or
#schizophrenia. But everything we say also may have applied to #ADD #OCD #anxiety moderate depression, #PTSD and more." (1/12)
@Metabolic_Mind I have seen it SIGNIFICANTLY improve or lead to remission in literally all of these disorders in my private practice and via my online Brain Fog Recovery Program. (2/12) #therapists #counselors #mentalhealthcounselor
@Metabolic_Mind It's ok to have hope that you can feel better. When you are suffering from any of these disorders, hope is a little scary. You don't want to be disappointed. Sometimes it's easier to practice acceptance of how you are feeling. (3/12) #hope #spoons #chronicillness
Read 12 tweets
Is the field of Metabolic Psychiatry new and emerging? Actually no. There has been a long history of metabolism being known to play a role in mental illness. #metabolicpsychiatry #mentalillness (1/12)
@ChrisPalmerMD provides an excellent outline of what we knew and when in this talk on the @Metabolic_Mind YouTube Channel (2/12)
@ChrisPalmerMD @Metabolic_Mind Sir Henry Modsley said in 1879 that diabetes is a disease that runs in families with insanity. #metabolism #metabolicpsychiatry (3/12)
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No Internal Monologue = #Calcified #PinealGland

'The lack of an inner monologue has been linked to a condition called aphantasia — sometimes called "blindness of the mind's eye.…
#Health #awakening
'several studies pointed out the relationship between the pineal calcification and #schizophrenia…
#sociopath #Narcissism
Read 5 tweets
"Many neurological diseases, such as Alzheimer’s disease, Parkinson’s disease, epilepsy, bipolar disorder, schizophrenia, and major depressive disorder are characterized by cerebral glucose hypometabolism, 🧵
insulin resistance, neurotransmitter imbalances, mitochondrial dysfunction, oxidative stress, and inflammation as potential causative factors."
#Alzheimers #Parkinsons #epilepsy #Bipolar #Schizophrenia #depression
Read 4 tweets
Pregnant women are advised not to clean their cat litter tray and to wear gloves while gardening.
Avoid eating raw meat or from eating unwashed fruit and vegetables.
This is to prevent the infection of Toxoplasmosis which is deleterious to the baby inside..
Toxoplasma Gondii is a parasite which can infect many mammals and birds, but can only sexually reproduce inside cats. Its normal lifecycle is to be shed into the environment in cat faeces, from where it may be picked up by rodents and birds, which are then eaten by cats..
For most people, it causes only a mild flu-like illness, but during pregnancy it can harm the fetus.
In people with weak immune systems, toxo can be deadly. .
Read 8 tweets
Schizophrenia research pioneer Robin Murray’s Keynote: excess dopamine synthesis in schizophrenia leads to the loss of ability to screen out unimportant stimuli; reading too much significance into unimportant things, “aberrant salience” #ICP2022
Stress or drug abuse also releases more dopamine: dopamine blocker medication can alleviate symptoms; with CBT (cognitive behavioral therapy) this can be successful in first episode psychosis up to 80% of the time #ICP2022
Many schizophrenia patients look back and develop insight but others may never regain insight; patiently talking with our patients is what good psychiatrists do
Read 12 tweets
I met an old lady who had #schizophrenia. She was on antipsychotics for more than 50 years. Never remitted. Had delusions of infidelity on her husband. He loved her and brought up his kids. The kids are grown up and married now.
She was also a cancer survivor. Docs repeated the same medicines as there weren't too many problems even though she was not fully well too.
I took a bold decision to start her on #Clozapine, a drug with risks but also better efficacy. Discussed with her and family.
They agreed to monitor her blood counts and the process started. She did well. Her delusion resolved. She smiled at her husband after long time. He was very happy to see her change. I was thrilled to see the joy in their family.
Read 6 tweets
From taking care of her Schizophrenic daughter to being president of the Schizophrenia Awareness Association & helping draft the Mental Healthcare Act in 2017 to authoring a book on mental illness, Amrit Kumar's journey has been inspiring for all.
@amritbakhshy Image
“When my daughter fell ill in 1991, I hadn’t even heard of schizophrenia. The internet was new, so I used it to go through Wikipedia and other portals for preliminary information. Image
Over the years, I have gained a lot of knowledge and experience. Image
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Robert Bransfield, MD: Thousands of peer-reviewed journal articles demonstrate the causal association between infections and #mentalillness 400+ peer reviewed scientific articles demonstrate the causal association between tick-borne disease and mental illness. #ILADS2022 #Lyme
2/Bransfield: Up to 40% of patients w/ #Lyme develop peripheral or central nervous system involvement. Psychiatric reactions include: #paranoia #dementia #schizophrenia #bipolar #panicattacks #depression #anorexianervosa, and #ODC #ILADS2022
3/Bransfield: Lyme is over represented in psychiatric patients. #ILADS2022
Read 15 tweets
Dempsey: Bartonella is a stealth multi-systemic infection transmitted by fleas, biting flies, body louse, mosquitoes and possibly ticks #ILADS2022 ImageImage
2/Dempsey: Objective findings of #Bartonella include fever, rash, swollen lymph nodes, uveitis #ILADS2022 Image
3/Dempsey: #Bartonella is multisystemic and can involve every organ. #ILADS2022 Image
Read 11 tweets
Are some diseases products of traits that are intrinsically vulnerable to failure? The deadline this Friday for #ISEMPH2022 abstracts inspires a deep dive into #schizophrenia genetics. @isemph @HumBehEvoSoc @BioengineerGM @rcpsych
In this week's Nature, Singh et al. report 10 ultra-rare variants that substantially increase the risk of schizophrenia, some more than 50 fold. Remarkable progress. Huge studies with deep sequencing are paying off! @RiadhAbed1 @ent3c @AllenFrancesMD…
In another landmark study published simultaneously, Trubetskoy, et al. report fine-mapping 287 common genomic loci each with small effects, but together accounting for substantial schizophrenia risk.…
Read 9 tweets
🖐️Have you ever seen those studies claiming finger length is related to health and behavior?

There's a whole field of research exploring the ratio between index and ring finger (known as 2D:4D digit ratio).

I think it's mostly #pseudoscience!

Take a few minutes and read on!👇
Before the debunking details, a disclaimer.

I care about scientific quality+integrity, & helping people understand the nuance behind abstracts & media headlines.

I'm not intending to disparage anybody personally. Perhaps some of this research is legit, but many issues w/ 2D:4D.
Supposedly #digitratio indicates prenatal testosterone exposure.

Fetuses exposed to more male sex hormones in utero are supposed to have a smaller digit ratio (shorter index finger or longer ring finger).

But, there's very little evidence of this in humans.
Read 33 tweets
(@manijadegarcia) #Compassion thread here, discussing ideas for survival, stress management, joy & healing using the acronym ACCESS to organize the ideas.

Be back after a break to dig in! 🥰


(@manijadegarcia) #Compassion to me is like creating welcoming, gentle internal space for the things I am #accepting—so I can be curious instead of judgemental about them. I'm reminded of indigenous views of trauma as "wisdom" & a "teacher," that can lead us to healing.

(@manijadegarcia) #compassion & #acceptance are closely related in my experience, like a bi-directional positive correlation, (increasing either can increase the other—try not to get hung up on stats "rules.") & #SelfCompassion is super powerful for general #MentalWellness.

Read 9 tweets
A disproportionate number of people with #Schizophrenia smoke vs the general population. Are they self-medicating with nicotine? Can #SaferNicotine products help them stop smoking?
Thread 🧵
A high strength nicotine e-cigarette has the potential to help people with schizophrenia spectrum disorders to quit or reduce smoking.…

Cognitive and early sensory alterations are core features of schizophrenia. A single dose of nicotine can improve those features in patients.…
Read 5 tweets
A short thread on a recent publication from @HiyaaLab, in Translational Psychiatry. The study shows that the dendritic structure & electrical properties of adult neurons in healthy brains depend on proactive regulation by the gene Tcf4, a high risk allele for #Schizophrenia.
1/7 Image
The #research reveals unexpected gene-networks, previously known to be involved in ciliary pathways, underlie #structural and #functional integrity of mature neurons in the healthy adult brain.
Given that the elaborate #dendrites & spines enable a neuron’s physical and electrical connectivity in a #neural circuit, alteration in the structure disrupts neuronal function, affecting the circuits and #cognition. 3/7
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Thank you all for holding space and sharing your stories. We are not alone in the trauma that we have dealt with, the impacts are not just on our academic career - it could be emotional too. My self esteem has been low & it stays there, all of the ableism almost confirms
not having as much value, maybe I deserved it, and I could be at blame since I am the common denominator in all the abuse. It is like being who I am is not okay and that is not okay. This society is toxic to exist as a disabled person compounding onto whatever we each manage 2/
every day for our health. I am the one who will go out of my way to support others and I have. I am CEO and co-founder here, I am a founder of @JADEdisjustice, a board member with @HealthAdvocateX, a social media manager for @academicvoices, co-founder of @dismhmatters, and
Read 16 tweets

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