Discover and read the best of Twitter Threads about #schizophrenia

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(@manijadegarcia) #Compassion thread here, discussing ideas for survival, stress management, joy & healing using the acronym ACCESS to organize the ideas.

Be back after a break to dig in! 🥰

[QT]

1/
(@manijadegarcia) #Compassion to me is like creating welcoming, gentle internal space for the things I am #accepting—so I can be curious instead of judgemental about them. I'm reminded of indigenous views of trauma as "wisdom" & a "teacher," that can lead us to healing.

2/
(@manijadegarcia) #compassion & #acceptance are closely related in my experience, like a bi-directional positive correlation, (increasing either can increase the other—try not to get hung up on stats "rules.") & #SelfCompassion is super powerful for general #MentalWellness.

3/
Read 9 tweets
#WorldMentalHealthDay
A disproportionate number of people with #Schizophrenia smoke vs the general population. Are they self-medicating with nicotine? Can #SaferNicotine products help them stop smoking?
Thread 🧵
1/
#WorldMentalHealthDay
A high strength nicotine e-cigarette has the potential to help people with schizophrenia spectrum disorders to quit or reduce smoking.
academic.oup.com/ntr/article/23…
2/
#WorldMentalHeathDay

Cognitive and early sensory alterations are core features of schizophrenia. A single dose of nicotine can improve those features in patients.

sciencedirect.com/science/articl…
3/
Read 5 tweets
Thank you all for holding space and sharing your stories. We are not alone in the trauma that we have dealt with, the impacts are not just on our academic career - it could be emotional too. My self esteem has been low & it stays there, all of the ableism almost confirms
1/
[QT]
not having as much value, maybe I deserved it, and I could be at blame since I am the common denominator in all the abuse. It is like being who I am is not okay and that is not okay. This society is toxic to exist as a disabled person compounding onto whatever we each manage 2/
every day for our health. I am the one who will go out of my way to support others and I have. I am CEO and co-founder here, I am a founder of @JADEdisjustice, a board member with @HealthAdvocateX, a social media manager for @academicvoices, co-founder of @dismhmatters, and
Read 16 tweets
My name is Eric. I'm a diagnosed schizophrenic with ASPD (AntiSocial Personality Disorder). Have you ever had a question about either of these disorders or what it is like to live with them? If so ask me. Let's end the stigma around these very misunderstood disorders.
@SweetInTheGale, @eroauthorPMQ, @The1stRedBeard

Let's see if this works better on this account.
Read 3 tweets
I'd go further in dereifying psych disorders by making clear they are just constructs that don't really take shape til we define them.

Eg What we call #schizophrenia could have been defined in dozens of different ways- no one of which would be much better than any other.
3 epistemological umpires:
#1 Naive realist (Spitzer)- "There are balls & strikes & I call them as they are"
#2 Constructionist (me)- "There are balls & strikes & I call them as I see them"
#3 Solipsist (Szsaz)- "No balls & no strikes til I call them"
Most DSM disorders are extremely valuable constructs- no more/no less.

Some DSM disorders are mistakes that shouldn't have been included.

No DSM disorder exists totally independent of how it has been defined & who defined it.
Read 4 tweets
#Thread
#Schizophrenia

A series of 7 short posts about schizophrenia. Written for Schizophrenia awareness week.
1
Is it one single well defined, well understood illness?
2
Some common types of schizophrenia described in #Marathi by fellow psychiatrist Dr Atul Dhage
Read 9 tweets
#WorldSchizophreniaDay
A thread to understand the basics.
The word "#Schizophrenia" was coined by the Swiss psychiatrist and eugenicist Eugen Bleuler in 1908, and was intended to describe the separation of function between personality, thinking, memory, and perception.
1/n
Let us understand the symptoms.
Delusions involve a firm, fixed, unshakeable belief which is not in keeping with the person's sociocultural setting and not amenable to reasoning
Hallucinations involve perception in the absence of a stimulus
2/n
Apart from that, there are disturbances in-
Language and speech processing
Auditory perception
Social interaction
Higher-order cognitive functions like decision-making, evaluating, brainstorming, and learning.
In short there are 5 major symptom domains-
3/n
Read 17 tweets
Thread in Marathi on #Schizophrenia on #WorldSchizophreniaDay
This is shared by a wonderful group of #MHPs that work towards fighting stigma in rural and semi-urban areas.
Read 4 tweets
1/32
The following respected scientific & public health organizations, with no industry ties, have reviewed the evidence and made public statements on the relative risk of #SaferNicotine vapes vs. toxic tobacco. There's rather a lot of them.
drive.google.com/file/d/1Ty7pgR…
THREAD
👇👇👇
2/32
Apparently, WHO EURO disagrees with @WHO @FCTCofficial. Weird.
3/32
WHO IARC thinks everything causes cancer. But they say nicotine vapes are safer than deadly cigarettes.
Read 34 tweets
Regular booster vaccines are the future in battle with #COVID19 virus, top genome expert says
Peacock told Reuters at the non-profit Wellcome Sanger Institute.
reuters.com/article/us-hea…
“The most successful educational approach to the Negro is through a religious appeal. We don’t want the word to get out that we want to exterminate the #Negro population!"😉🙈
Margaret #Sanger was sponsored by #Rockefeller.

americamagazine.org/politics-socie…
1936, #Rockefeller's Dr. Franz Kallmann interrupted his study of hereditary degeneracy and emigrated to America because he was half-Jewish. He established the Medical Genetics Department of the NY State Psychiatric Institute

freemasonrywatch.org/rockefeller_fo…  
Read 15 tweets
Toronto’s Marty Verlaan is one of 300,000 Canadians living with schizophrenia. This is his story.

Film: The Man Who Walks Backwards
Directed by: Stephen Hosier
Learn More: torstar.co/W0Ig50DkBd2

@SchizophreniaCa #BellLetsTalk #schizophrenia #mentalhealth
“I just wanted to tell Marty’s story and show people that someone like Marty walking backwards on the street might seem a little peculiar at first. But he’s got a past, he’s got a present and he has a future," Hosier said.

thestar.com/news/gta/2021/…
In the film, Marty reveals how he became estranged from his family — his wife and two kids — and hopes to be reunited with them someday, how he began hearing voices and how, about 11 years ago, he began walking backwards.

📷: Thomas Skrlj

thestar.com/news/gta/2021/…
Read 6 tweets
#MedicalNicotine

348,601 "ever-#snus users had about 60% lower Parkinson's disease risk compared with never-snus users."
academic.oup.com/ije/article/46…

30,000 British doctors followed for 60 years: "current smokers at baseline had a 30% lower risk of PD."
n.neurology.org/content/neurol…
#MedicalNicotine

Nicotine is beneficial for people with #ADHD. Research on adults and adolescents with ADHD shows that nicotine patches improve focus and attention, and reduce hyperactivity & impulsivity.
#MedicalNicotine

Nicotine reduces symptoms of Alzheimer's disease (AD).
d1wqtxts1xzle7.cloudfront.net/48014043/bf001…
Read 11 tweets
ADHD: "Nicotine ...may have properties similar to stimulant medications (e.g., Ritalin) used to treat ADHD. [It] may increase attention and reduce hyperactivity & impulsivity."
clinicaltrials.gov/ct2/show/NCT00…
#MedicalNicotine #ADHD #ADHDAwareness #Autism #Neurodiversity #Neurodivergent
ADHD: "The positive relation between ADHD & nicotine dependence is best explained by the self-medication hypothesis. This hypothesis ...is supported by ample evidence."
tandfonline.com/doi/pdf/10.108…
#MedicalNicotine #ADHD #ADHDAwareness #Autism #Neurodiversity #Neurodivergent
Read 5 tweets
Fascinating @JAMANetworkOpen article on #schizophrenia treatments .. limits of #pharmacotherapy and benefits of added #psychosocial treatments. Here’s a snippet with eye towards how this relates to treating other mental health conditions. 1/4 @division_55
jamanetwork.com/journals/jama/…
“Among responders (to meds), some are able to function independently, others remain disabled despite control of their psychotic symptoms...residual disability attributed to negative symptoms and cognitive deficits, which are less responsive than psychosis to drug treatments.” 2/4
“persistence of disability and ↘️ quality of life, poor medication adherence necessitated delivery of evidence-based psychosocial services, including CBT; family psychoeducation; social skills training; assertive community treatment; and assistance w/work, education, housing” 3/4
Read 4 tweets
1/ #22q11DS is a rare genetic disorder. Due to the missing of a small piece of chromosome 22 (="deletion"), it can lead to a range of physical issues, most often affecting the heart, palate and immune system.

It can also impact the brain. How?
images.app.goo.gl/oKK5xqaVFDhVkC…
2/ The missing bit of chr22 contains amongst others instructions for the developing brain.

Imagine you are putting together an IKEA cabinet, but part of one page of the manual is missing.
images.app.goo.gl/g9Skks5aWbTimE…
3/ You'd be able to put it together, but likely with some difficulty. Maybe one of the doors doesn't close tightly, or a shelf is wobbly.
Likewise, 22q11DS can affect the development of the brain. This has consequences for the person with this genetic variant.
Read 11 tweets
How do the hundreds of genetic risk-factors for #Schizophrenia actually lead to disease? New work medrxiv.org/content/10.110… from @manoliskellis illuminates the #SingleCell landscape of #Brains from patients with #Schizophrenia and their healthy counterparts🔬🧠🧵1/10
Combining single-nuclear RNA-Seq @10xGenomics, barcode #ing, and multi-level cell-state decomposition, first author Brad Ruzicka et al. identify 20 cell types in the prefrontal cortex of 24 patients with #Schizophrenia and 24 controls 2/10
While most of these #cells have been described before, what's powerful about the approach is that we can now ask: are there specific cell-types that are increased or decreased in numbers in #Schizophrenia patients compared to healthy individuals (great study design) 3/10
Read 10 tweets
1/X rdcu.be/b992F
We are very excited about our study appearing today in @NatureMedicine. It is a genotype-phenotype study in the largest sample of individuals with #22q11.2 deletion syndrome reported to date.

Let us give you a quick 12-step tour of our findings.
2/X #22q11DS is a #RareDisease. In addition to a range of physical symptoms, patients are liable to neuropsychiatric conditions, including #schizophrenia (SZ) and #intellectualdisability (ID). However, manifestations are highly variable. Image: positiveexposure.org
3/X With the International 22q11 Brain and Behavior Consortium (IBBC), we examined the role of common genetic variation, summarized in a polygenic score (PS) in the context of the 22q11.2 deletion. @NIMHgov @WiringTheBrain @EricTopol @22qFoundation @UCLAHealth
Read 13 tweets
We are thrilled to share our #preprint "Atlas of genetic effects in human #microglia transcriptome across brain regions, aging and #disease pathologies"!
Work led by @lopeskp @JackHumphrey_ #Gijsje and others from #deWitte and #Raj Lab (@towfiqueRaj)
t.ly/pZqQ 1/23
Here, we describe the Microglia Genomic Atlas (#MiGA) project. A genetic and transcriptomic resource of 255 primary human microglia isolated from 4 brain regions of 100 donors with neurodegenerative and psychiatric disease and controls. 2/23 Image
We performed the following analysis: I) age-related (the age of donors range from 21 to 103 y.o! II) brain regional heterogeneity ; III) expression and splicing quantitative trait loci #eQTL & #sQTL. 3/23
Read 23 tweets
I now know why my colleague mentioned @Rufusmay to me.

I love the way he proposes telling stories, and being creative, playful and vulnerable as a way of bringing our whole selves to our work.

Highlights below...

1/20
2:00 2:35

"Until you or a relative experience it, it's another world [...] If you're sectioned you lose your rights, and things get done to you...

...I think it really changed my life."

On the influence of experiencing involuntary treatment on his career.

2/20
2:35 - 3:05

"When I managed to return to education I thought, "I want to make a difference" and go back into the #mentalhealth system and promote a more listening approach...

...I didn't feel I'd been listened to."

3/20
Read 21 tweets
1/ Our work out today in @PNASNews: even 60 years later, we are still seeing increased risk of #Tuberculosis among those who experienced prenatal exposure to the Great Chinese #famine (1958-62), w/ @Trangucc @kbratnelson @jzelner @Justin_Remais and others pnas.org/content/early/…
2/ Previous research has linked prenatal exposure to famine to increased risks of a range of chronic conditions (e.g., #Schizophrenia, type 2 #diabetes, and #hypertension)
Read 10 tweets
Great paper by @HelenaRoennfel2 and @DrLouiseByrne on senior staff's understanding of #livedexperience workforce issues: publish.csiro.au/ah/Fulltext/AH…

I particularly ❤️ Sam:

"...But you know just saying ‘you’re not recovered enough to do this job’ is a load of bullshit." (Sam)
"The ambiguity in this study reinforces the need for greater consensus in defining and determining relevant lived experience in the context of designated roles."

As someone who has previously been responsible for recruiting peer workers, I was less interested in what... 1/2
...experiences they had had, and more interested in what they had learnt from those experiences that might help them to connect with and support others, especially their capacity to work with people who may have different experiences and worldviews to their own. 2/2
Read 6 tweets
(1/9) Despite widespread bipartisan opposition & amid #COVID19 concerns, the fed govt executed #DannyLee on Monday, is pursuing the execution of #WesleyPurkey today, and has scheduled execution for #DustinHonken on 7/17, and #KeithNelson later this summer.
(2/9) Today, a fed court temporarily blocked the execution of #WesleyPurkey, who has #Alzheimers, #schizophrenia and other issues. As @RonHonberg wrote: “The federal courts must step in now to prevent this unconstitutional execution from taking place” newsweek.com/execution-fede…
(3/9) New from @ACLU: The execution of Danny Lee yesterday represented a dangerous miscarriage of justice, but it isn't the last we face this week. This is an important read to understand why federal executions are so broken. cnn.com/2020/07/14/opi…
Read 9 tweets
#Fascism focuses on a grandiose past of an in-group, violence done over centuries by out-groups, a fear of loss of identity, identifying a nation/some other out-group [minority etc] as an "enemy".

For resurrection to happen,a strong Leader, divinely ordained,is necessary.
Fascists never think they are fascists. A fascist never thinks of himself/herself as a “fascist”, anything at all carrying a negative or malicious connotation. They think of themselves, first,as victims.Victims of great and grand conspiracies — the Jews,
the Muslims,the Mexicans
Read 14 tweets

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