Thread by @nick_krontiris

In this one, an 8-hour time-restricted eating (TRE) protocol was not associated with additional benefits for reducing intrahepatic triglyceride content, body fat and metabolic risk factors compared with daily calorie restriction in adults with obesity and NAFLD.

- All participants were instructed to follow a diet of 1500 to 1800 kcal/d for men and 1200 to 1500 kcal/d for women.

- The diets were composed of 40% to 55% carbohydrate, 15% to 20% protein, and 20% to 30% fat.

- Participants assigned to the TRE group were instructed to consume the prescribed calories from 8:00 am to 4:00 pm every day, and only noncaloric beverages were permitted outside of the daily eating window.

- Participants in the DCR group had no eating time restriction during the 12-month study period.

- The 8-hour TRE was no more effective in reducing the intrahepatic triglyceride content and in achieving resolution of NAFLD among patients with NAFLD compared with habitual meal timing with the same caloric intake restriction.

- Both diets produced comparable effects in reducing body weight, waist circumference, body fat and visceral fat.

- Both diets were equally effective in reducing blood pressure, plasma glucose level, HOMA-IR, liver enzyme levels, and lipid levels during 12 months.

Effects of Time-Restricted Eating on Nonalcoholic Fatty Liver Disease: The TREATY-FLD Randomized Clinical Trial (open access)

doi.org/10.1001/jamane…

#weightloss #nutrition #diet