The findings of this one suggest indicate no individual or additive benefit of higher dietary quality on working memory during a 2-year calorie restriction period in healthy adults without obesity and a mean age of 38.1 years. 
- The study tried to evaluate the association between dietary quality and spatial working memory in healthy adults without obesity (aged 21–50 y) during a 2-year calorie restriction intervention.
- Two dietary pattern indices with different underlying principles were used: 1) the Dietary Inflammatory Index (DII), which is a validated tool designed to assess the inflammatory potential of individual diets...
...and 2) the Healthy Eating Index (HEI) as an index of dietary quality that is highly correlated with the DII.
- Analysis found no statistical association between the 2 established dietary indices and spatial working memory, a key measure of cognitive function that declines with age.
- In addition, there was no evidence of an effect of caloric resitriction on spatial working memory compared to the Control group.
- "Consuming a healthful diet, particularly a low-inflammatory diet, and practicing CR have been posited to improve cognitive function...
"...However, our findings did not indicate an association between dietary patterns and cognition assessed during the 2-y CALERIE trial of human CR in individuals without obesity."
No Effect of Calorie Restriction or Dietary Patterns on Spatial Working Memory During a 2-Year Intervention: A Secondary Analysis of the CALERIE Trial (open access)
doi.org/10.1016/j.tjnu…
#weightloss #nutrition #diet
doi.org/10.1016/j.tjnu…
#weightloss #nutrition #diet
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