Matthew Kavanagh Profile picture
Apr 3, 2023 16 tweets 6 min read Read on X
Our NEW @Global_Policy article out as #PandemicAccord negotiators meet: "Vaccine Politics: law & inequality in COVID" shows COVAX failed b/c of a model misaligned with politics.Not $.Not tech.
Same approach,better funded ≠ equity next pandemic
🧵thread onlinelibrary.wiley.com/share/author/S… Image
I write w/@Renu_Singh_ about why the dominant law&policy paradigm proved incapable of securing equity.
Political analysis necessary to design effective pandemic response.
Greater use of law, inter-state negot, and intl agreements can engage intl & domestic political forces 2/16 Image
Well before a vaccine had been developed there was an unprecedented moment where heads of state and global leaders pledged they would ensure equitable access to a not-yet-created medical countermeasure. But of course... 3/16 Image
…those efforts failed to ensure anything approaching equity. A yr after vaccines registered, 9 bill doses delivered, only 1% to low-income countries. 1 in 4 African health workers were vaxed but 72% of entire W European pop had been. COVAX reached >half goal of 2b doses 4/16 Image
Why did equity efforts fail? We trace development of 2 competing law & policy paradigms. 1 focused on voluntary measures (little use of legal mechanisms), norm entrepreneurship, and aggregating demand (COVAX). Unit of debate/sharing was doses. 5/16
An alternative paradigm proposed by Southern leaders focused on openness, sharing technology instead of doses, & on use of law and agreements between states to compel sharing of tech to produce independently in factories throughout the world 6/16 Image
Paradigms could have been combined, mutually reinforcing. Wealthy states (e.g. US) used elements of both voluntary/demand and compulsory/tech sharing. But powerful ACT-A players had policy preferences against tech sharing/compulsory legal measures. 7/16 Image
.@SuerieMoon et al explain the role of governments in ACT-A decisionmaking was problematically unclear; in particular, LMIC govts only appear in governance months into the effort while industry was "initially in a leading role." This mattered… 8/16
thelancet.com/journals/lance…
… it reflects govts never had a single venue where they negotiated access proposals and paradigms. In the absence of that, two paradigms grew apart, demand-focused/ voluntary action dominated and default was against use of law or legal agreements to share tech 9/16
Problem was VACCINE NATIONALISM was entirely PREDICTABLE to anyone watching domestic politics in powerful states or familiar with Intl Relations in context of existential threats.
Dominant voluntary paradigm had no viable mechanism to counter vaccine nationalism 10/16
Rising populism, Xi and Trump govern largest economies.Even in countries promising cooperation (Europe,Canada) leaders promised rapid vax for all, put in orders for many times more than needed and used their political & economic power to secure those doses. 11/16 Image
No major state power said “our young, healthy will wait for others before we vax health workers and elderly”
No major manufacturer had an incentive to tell the richest, most powerful countries (home to their biggest markets and regulatory masters) to wait. 12/16
Lesson: Norms for sharing doses are too weak to overcome nationalism in pandemic crisis; Leaders’ domestic political incentives=against sharing doses. Instead: manufacturing in regions so all can make for “their own” & have agreement between states to share necessary tech 13/16
Some want to make this model permanent. But it failed. Not b/c there wasn’t ready financing. Or b/c of technical issues. It was missing a political analysis & the legal mechanisms necessary to address vaccine nationalism.
We must not repeat this mistake in next pandemic. 14/16
We need for more law to address known political realities:
➡️agreements between states
➡️law to compel companies to share tech
➡️use of legal mechanisms between states to (at least) complain formally when agreement to share tech isn’t fulfilled
15/16
Also: every global health initiative needs a serious political analysis…
Thanks for reading @Global_Policy
onlinelibrary.wiley.com/share/author/S…
/fin Image

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More from @MMKavanagh

Jul 6, 2023
Interesting on ethics in #PandemicTreaty. But I'm baffled by @G_Owen_Schaefer @ZekeEmanuel et al take on Intellectual Property. Seems to misunderstand what’s happened in actual pandemics; if dont open monopolies, their other (good) countermasure ideas won't work... a thread. 1/12
They suggest IP is needed for “sustainability” principle & waiving IP = ethical problm b/c “policy makers would then face a tension between short-term human wellbeing, equity, and solidarity, & the long-term sustainability of incentives to respond to future pandemics"True? 2/12
It does not hold up. Why?
First big issue: their reasoning relies on the idea we need to solve problem of vaccine, drug, diagnostic makers lack of incentives. But in real life, these companies had plenty during COVID-19 in the form of 1)direct public investment and 2) profit
3/12
Read 12 tweets
Nov 10, 2022
HIV treatment as cautionary tale for economists.
1. no excuse. By 2005-7 Oster speaking/writing against treatment, antiretrovirals avail for 8 years.Finally reaching 1 mill ppl in Africa. Deaths long ago dropped in US/Europe (L) finally falling in E/SAfrica. She argues to stop... ImageImage
2. Entire basis for cost-effectiveness calculations based on 2 false ideas. The first was confusing price for cost and not understanding it was subject to govt action. Price=a choice. Generics reverse-engineered & govts used power to import. Cost fell 99% to >$200. Image
3. Second false idea: Treatment and prevention are either/or choice. Its just wrong. a)ARVS stop HIV transmission b)Treatment brings hope, encourages testing, opens a key gate for prevention. The "do education instead" idea was not viable, and that had been well shown by 2005...
Read 9 tweets
Jan 22, 2022
Is it “not clear that 'coloniality' is the cause” of COVID19 vaccine inequality? Maybe not for many (helpful article in that sense), let's discuss.
THREAD🧵#decolonizing starting w political economy: $trillions for North's corporate, R&D, university "capacity" has an origin.../1
First: colonialism was a system of resource extraction, slave trade, and global commerce that enriched the global North and has had long-running harm for Southern economies… inequality in resources is not naturally occurring/2
Empiricaly clear e.g. Nunn "the world’s current income differences could be explained by the divergent effects of European contact globallty, which resulted in a massive transfer of disease, food, ideas, and people.../3
science.org/doi/10.1126/sc…
Read 15 tweets
Aug 4, 2021
Article out: Legal environ & #pandemic response. After 5yr global #HIV push on testing&treatment, countries that criminalized gay relat, sexwork, drugs had less success. Rights-protective laws, better outcomes
Biomedical & structural interconnected
A🧵/1
gh.bmj.com/content/6/8/e0… Image
Measuring legal approaches in world: @HIVPolicyLab data show some countries highly criminalize, some less so (only 20% criminalize all). Meanwhile rights-protective legal approaches: 23% have strong non-discrim, 39% ind. human rights inst., 79% enforceable GBV laws. /2 Image
@HIVPolicyLab @BenjaminMMeier @sharifasekalala @SECTION27news @mpactglobal @mplngr @KashishAneja_ @EllieGraeden @LawrenceGostin We looked at success on the global #HIV 90-90-90 targets to achieve knowledge of status + viral suppression by 2020. Biomedical focus of last 5 year Global AIDS Strategy agreed at UNGA. Some countries exceeded, many did not. This allows for empirical comparison. /3
Read 7 tweets
Jun 21, 2021
Dear @JoeBiden @KamalaHarris @SecBlinken @SecBecerra time for you to act. Sharing tech is good public health, it's good diplomacy. NIH-Moderna vax already paid for. It could show the power and relevance of government, US in particular. How about you...
1. Democratize vaccine production. I know you've already said USDFC is investing, take the last steps... and also
foreignpolicy.com/2021/03/01/to-…
2. Use the authority you have. Not sure why you're NOT using the carrot and stick to get this done, but it's a bad look. Moderna has NO interest in these markets, has not even registered to sell there. You can use the Defense Production Act and...
lpeproject.org/blog/how-to-va…
Read 4 tweets
Jun 21, 2021
#Covax is failing. Big picture: even as delivers doses, it won’t deliver goal of EQUITY.
Short term: By June was to reach just 3% of LMIC pops. Delivered only 1/4 of that (88 of 337m forecast).
We need to talk about why & learn real-world, politically-informed lessons
🧵[thread]
The goal: at a high level, COVAX as a pillar of ACT-A aimed to “ensure that every country gets fair and equitable access to eventual #COVID19 vaccines…. By acting as an insurance policy.” At this point, it's clear this model has not been successful /2
Not #VaccinEquity: Dec 2, 11, 21 of 2020 UK, US & EU authorized #COVID19 vaccine.
6mos later, so many ways (data, stories, lives) to see inequity outcome of current vaccine prod & distrib systems.
Here's 👇from @fibke:% pop vs % vax does NOT approach equity /3
Read 21 tweets

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