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Circadian rhythms are important for successful #MCAS treatment.
Lifestyle patterns that mess w/your clock will also mess with clock control of mast cell activation leading to an 'always on' state as opposed to one that fluctuates (not good).
1/n
jstage.jst.go.jp/article/allerg…
Lifestyle patterns that mess w/your clock will also mess with clock control of mast cell activation leading to an 'always on' state as opposed to one that fluctuates (not good).
1/n
jstage.jst.go.jp/article/allerg…
"Environmental and lifestyle factors that disturb the normal rhythmicity of the circadian clock, such as irregular eating habits, can lead to the loss of circadian control of mast cell activation.
2/n
2/n
Consequently, the degree of mast cell activation becomes equally strong at all times of day, which might clinically result in worsening allergic symptoms. Therefore, further understanding of the association between mast cell activation and 3/n
the circadian clock is important to better manage patients with allergic disease in the real world, characterized by a “24/7 society” filled with environmental and lifestyle factors that disturb the circadian clock rhythmicity." 4/n
The interplay between mast cells, pineal gland, and circadian rhythm: Links between histamine, melatonin, and inflammatory mediators
onlinelibrary.wiley.com/doi/pdf/10.111…
onlinelibrary.wiley.com/doi/pdf/10.111…
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