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Apr 23 4 tweets 2 min read Twitter logo Read on Twitter
This one failed to find an effect of long-term (24 weeks) daily administration of intranasal insulin at 40IU once daily on food intake, appetite, and weight in older adults with a mean age of 65.5 years, either with or without type 2 diabetes. Image
- A null effect of 24 weeks daily administration of 40 I.U. of intranasal insulin once daily on food intake, appetite, and weight in older adults was observed.
- Similarly, there were no differences in the effect of intranasal insulin when comparing men to women, obese to lean participants, and diagnosis of type 2 diabetes.
Daily intranasal insulin at 40IU does not affect food intake and body composition: A placebo-controlled trial in older adults over a 24-week period with 24-weeks of follow-up

doi.org/10.1016/j.clnu…

#nutrition #diet #Obesity #MetabolicSyndrome #appetite

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More from @nick_krontiris

Apr 24
The findings of this one suggest that acute evening HIIT may partially reduce the detrimental effects of partial sleep restriction on long-term declarative memory. Image
- Some studies have shown that short sleep duration (<7 hours per night) is associated with adverse health outcomes and impaired cognitive functioning including poor attention, decreased concentration and impaired memory.
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Apr 24
The findings of this one suggest that the positive effect of exercise on cancer might be partly due to immune cell mobilization, as a single bout of acute exercise of only 10 min was associated with leukocytosis in breast cancer patients. Image
- The study examined the effect of acute exercise on blood immune cell counts in newly diagnosed breast cancer patients who had not yet started any treatments.
- Acute exercise increased the number of total leukocytes (CD45+), CD8+ T cell, CD19+ B cells, total NK cells, CD56+CD16+ NK cells, and intermediate (CD14+CD16+) monocytes.
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Apr 24
Interestingly, the findings of this one in mice suggest that muscle mass and myofiber type are regulated at different gravitational thresholds. Image
- Findings suggested that artificial gravity equivalent to lunar gravity (1/6 g) is sufficient to suppress microgravity-induced atrophy of the soleus muscle.
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Apr 24
This systematic review and meta-analysis suggests that adherence to a healthy lifestyle is likely to reduce the risk of breast cancer.
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- Most of the prospective studies included five variables in the index : diet, physical activity, alcohol and tobacco consumption and BMI...
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Apr 24
The findings of this one suggest that the glycaemic load of a meal is not a major determinant of postprandial response, with a greater impact exerted by the metabolic health of the individual. Image
- The aim of this study was to perform an acute cross-over intervention to examine the interactive actions of meal glycaemic load on the dynamic responses of the plasma metabolome in overweight females.
- Postmenopausal women with a mean age of 63 yeras ingested two differing high-carbohydrate test meals (73 g carbohydrate; 51% energy) composed of either low glycemic index or high glycemic index foods in a randomised sequence.
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Apr 24
Using data from 4 different cohorts, this one found positive associations between sugar-sweetened beverages & low/no-calorie beverages intake and NAFLD, as assessed using the Fatty Liver Index (FLI) (≥60). Image
- The study used data from 42,024 participants from the Lifelines Cohort study (Lifelines; The Netherlands), the Nutrition Questionnaire Plus study (NQPlus; The Netherlands), the PREDIMED-Plus study (PREDIMED-Plus; Spain), and the Alpha Omega Cohort (AOC; The Netherlands).
- Harmonized data analyses of showed positive associations between sugar-sweetened beverages & low/no-calorie beverages intake intakes and FLI-defined NAFLD prevalence.
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