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Nick Krontiris Profile picture
@nick_krontiris
Apr 23 • 4 tweets • 2 min read Twitter logo Read on Twitter
This one failed to find an effect of long-term (24 weeks) daily administration of intranasal insulin at 40IU once daily on food intake, appetite, and weight in older adults with a mean age of 65.5 years, either with or without type 2 diabetes. Image
- A null effect of 24 weeks daily administration of 40 I.U. of intranasal insulin once daily on food intake, appetite, and weight in older adults was observed.
- Similarly, there were no differences in the effect of intranasal insulin when comparing men to women, obese to lean participants, and diagnosis of type 2 diabetes.
Daily intranasal insulin at 40IU does not affect food intake and body composition: A placebo-controlled trial in older adults over a 24-week period with 24-weeks of follow-up

doi.org/10.1016/j.clnu…

#nutrition #diet #Obesity #MetabolicSyndrome #appetite

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More from @nick_krontiris

Nick Krontiris Profile picture
Apr 24
The findings of this one suggest that acute evening HIIT may partially reduce the detrimental effects of partial sleep restriction on long-term declarative memory. Image
- Some studies have shown that short sleep duration (<7 hours per night) is associated with adverse health outcomes and impaired cognitive functioning including poor attention, decreased concentration and impaired memory.
- The objective of this study was to estimate the extent to which a remote, evening HIIT intervention performed in the evening prior to encoding (learning) would compensate for the negative effect of sleep restriction...
Read 16 tweets
Nick Krontiris Profile picture
Apr 24
The findings of this one suggest that the positive effect of exercise on cancer might be partly due to immune cell mobilization, as a single bout of acute exercise of only 10 min was associated with leukocytosis in breast cancer patients. Image
- The study examined the effect of acute exercise on blood immune cell counts in newly diagnosed breast cancer patients who had not yet started any treatments.
- Acute exercise increased the number of total leukocytes (CD45+), CD8+ T cell, CD19+ B cells, total NK cells, CD56+CD16+ NK cells, and intermediate (CD14+CD16+) monocytes.
Read 8 tweets
Nick Krontiris Profile picture
Apr 24
Interestingly, the findings of this one in mice suggest that muscle mass and myofiber type are regulated at different gravitational thresholds. Image
- Findings suggested that artificial gravity equivalent to lunar gravity (1/6 g) is sufficient to suppress microgravity-induced atrophy of the soleus muscle.
- However, microgravity-induced slow-to-fast myofiber-type transition in the soleus muscle was not prevented by lunar gravity.
Read 5 tweets
Nick Krontiris Profile picture
Apr 24
This systematic review and meta-analysis suggests that adherence to a healthy lifestyle is likely to reduce the risk of breast cancer.
- The main components included in the healthy lifestyle indices were: diet, physical activity, alcohol consumption and body mass index (BMI); followed by tobacco consumption, supplements use, and breastfeeding.
- Most of the prospective studies included five variables in the index : diet, physical activity, alcohol and tobacco consumption and BMI...
Read 8 tweets
Nick Krontiris Profile picture
Apr 24
The findings of this one suggest that the glycaemic load of a meal is not a major determinant of postprandial response, with a greater impact exerted by the metabolic health of the individual. Image
- The aim of this study was to perform an acute cross-over intervention to examine the interactive actions of meal glycaemic load on the dynamic responses of the plasma metabolome in overweight females.
- Postmenopausal women with a mean age of 63 yeras ingested two differing high-carbohydrate test meals (73 g carbohydrate; 51% energy) composed of either low glycemic index or high glycemic index foods in a randomised sequence.
Read 9 tweets
Nick Krontiris Profile picture
Apr 24
Using data from 4 different cohorts, this one found positive associations between sugar-sweetened beverages & low/no-calorie beverages intake and NAFLD, as assessed using the Fatty Liver Index (FLI) (≥60). Image
- The study used data from 42,024 participants from the Lifelines Cohort study (Lifelines; The Netherlands), the Nutrition Questionnaire Plus study (NQPlus; The Netherlands), the PREDIMED-Plus study (PREDIMED-Plus; Spain), and the Alpha Omega Cohort (AOC; The Netherlands).
- Harmonized data analyses of showed positive associations between sugar-sweetened beverages & low/no-calorie beverages intake intakes and FLI-defined NAFLD prevalence.
Read 9 tweets

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