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[CASE REPORT] The CDC reports a case of Borrelia miyamotoi in California man: The Center for Disease Control (CDC) just published a case report In their journal, Emerging Infectious Disease, of Borrelia miyamotoi in California (continued in comments). #Lyme #Lymedisease #TBRF
1/7 The man was on a drug for multiple sclerosis, so he was considered immunocompromised. He experienced fevers that lasted a day, every 10-14 days, nausea, and “visual changes.”
2/7 Borrelia miyamotoi is a close cousin of Lyme disease and part of the tickborne relapsing fever group (TBRF).
3/7 When I read this report, many thoughts came to mind. First, it is remarkable to see so many local, state, and national health agencies involved in a case of a tickborne infection. It was as if a novel infection was being discovered.
4/7 Borrelia miyamotoi is not rare. A 2018 study demonstrated that 27% of blood samples tested in Californians suspected of having Lyme disease were positive for tickborne relapsing fever (TBRF). B. Miyamotoi is only one of the species in the group.
5/7 The report cites a study that found only two positive blood samples of B. Miyamotoi out of 1700 blood donors in California. However, the screening test used in the study has very low sensitivity, so it would produce many false negative results.
6/7 About five years ago, the tickborne-specific laboratory Igenex developed a sensitive immunoblot test for the tickborne relapsing fever group. Since using this test, about a quarter of my patients tested for tickborne infections are positive for TBRF.
7/7 Source: wwwnc.cdc.gov/eid/article/29…
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