[NEW REVIEW] Is immune cell exhaustion responsible for #MECFS?: Many people report the onset of #myalgicencephalomyelitis/#chronicfatiguesyndrome (ME/CFS) following an infectious-like illness, suggesting a persistent infection may be the cause (continued in comments). 1/5 Cellular metabolic dysfunction has also been implicated in ME/CFS. Chronic infections affect cellular metabolism, and cellular metabolism influences cellular function. However, immune cell exhaustion has not been explored in ME/CFS.

[NEW RESEARCH] New findings associating #MECFS and #LongCOVID: A new preprint publication by 35 authors, including leading ME/CFS researchers Bob Naviaux and Bhupesh Prusty, identified a common biomarker pattern between ME/CFS and Long COVID (continued in comments). #COVID19 1/5 Identifying these biomarkers has significant benefits since diagnostic markers have yet to be identified.

[RESEARCH] Mitochondrial function is critical for proper immune response: #Mitochondria are often thought of as the powerhouse of the cell and their role in energy production (continued in comments). #chronicillness #chronicLyme 1/5 Because of the immune system’s high energy requirement, mitochondria play an essential role in an effective immune response.

NEW RESEARCH: Fibronectin causes #Lyme and #Bartonella adhesion to blood vessel walls. Successful infection depends on the bacteria’s ability to adhere to cells and avoid the immune system (continued in comments). #Lymedisease pubmed.ncbi.nlm.nih.gov/37343664/ 1/6 Adhesion of bacteria to the host’s cells is the first step in establishing an infection, followed by colonization, replication, persistence, and release of virulence factors to disseminate the infection.

[CASE] Autoimmune #Scleroderma associated with Mercury, #Mold, and #Babesia: I recently saw a 50-year-old female suffering from joint pain, stiffness, muscle weakness, and poor circulation (continued in comments). 1/8 Recently, she began to have trouble swallowing. About ten months ago, she saw a rheumatologist who diagnosed her with scleroderma.

Does SOT work for #Lymedisease? SOT stands for supportive oligonucleotide therapy, originally called anti-sense oligonucleotide therapy (AOT). Creating a patient’s SOT treatment is done by sending their blood to a laboratory in Greece (continued in comments). #Lyme 1/4 The lab attempts to identify the primary genetic sequence of target genes, in this case, Lyme. The lab then creates an “anti-copy” of the replication sequence of the gene. There are additional steps in creating an individual’s SOT before administering intravenously.

There are over 400 peer-reviewed articles discussing the association between #Lymedisease and neuropsychiatric symptoms (continued in comments). #LymeDiseaseAwarenessMonth #Lyme 1/4 The biggest challenge for people suffering from mood disorders is most mental health practitioners are not trained to look for the underlying cause(s) of the symptoms – including Lyme disease.

The Cytokine IL-6 in COVID-19 & Reducing It with Turmeric: The cytokine interleukin-6 (IL-6) has been associated with the severity of #COVID19 (continued in comments). #COVID 1/5 A meta-analysis of multiple studies demonstrated IL-6 levels are 2.9 fold higher in patients with complicated COVID19 compared to people with uncomplicated COVID19. A study using the IL-6 blocking drug tocilizumab confirmed improved outcomes in patients with COVID19.

[CASE REPORT] Brain biopsy detects #Bartonella in brain lesions: A 28-year-old woman presented to the neurology department with progressive vision loss in both eyes over the prior four months (continued in comments). #Lyme #Lymedisease pubmed.ncbi.nlm.nih.gov/37153245/ 1/5 She had a history of #lupus and had been on high-dose prednisone. A brain MRI showed numerous lesions in her cerebral and cerebellar hemispheres.

The Six Cardinal Elements of the Health Cycle: Naviaux's recent paper discussing mitochondrial and metabolic features of salugenesis and the healing cycle emphasizes that #chronicillnesses persist due to an "abnormal persistence of a normal phase of the healing cycle." #MECFS 1/3 Naviaux outlines six "cardinal elements" of the health cycle: restorative sleep, wakeful activity, nutrient intake, waste and toxin removal, social connection, and nature connection.

NEW RESEARCH: Herbal and enzyme formula effective at reducing #Biofilms. Biofilms are a polysaccharide matrix secreted by microbes to create a protective community. Think of a biofilm like Jello surrounding a raspberry in a dessert (continued in comments). #Lymedisease #Lyme 1/5 Biofilms can make bacteria up to a thousand times more resistant to antibiotics. #Candida and #Borrelia (the bacteria that cause Lyme disease) commonly produce biofilms.

[CASE REPORT] The CDC reports a case of Borrelia miyamotoi in California man: The Center for Disease Control (CDC) just published a case report In their journal, Emerging Infectious Disease, of Borrelia miyamotoi in California (continued in comments). #Lyme #Lymedisease #TBRF 1/7 The man was on a drug for multiple sclerosis, so he was considered immunocompromised. He experienced fevers that lasted a day, every 10-14 days, nausea, and “visual changes.”

How do you know if you have #Dysautonomia/#POTS? 1/6 Dysautonomia/POTS is a common concomitant condition in complex #chronicillness. Normally our #autonomicnervoussystem (#ANS) responds to changes in position from lying or sitting to standing.

The Effect of #Glyphosate on the #Gutmicrobiome and Neurocognitive Function
sciencedirect.com/science/articl… 1/5 Glyphosate is the active ingredient in the herbicide #RoundUp. In 1996 #geneticallymodified soybeans that could tolerate Round Up were introduced. At that time, Round Up made up just 3.8% of herbicides in use. By 2007 glyphosate use was more than double the next herbicide.

Mercury causes release of #mastcell mediators #MCAS
pubmed.ncbi.nlm.nih.gov/20222982/ 1/4 There is a lot of discussion about what causes #mastcellactivationsyndrome. Rarely are toxic metals such as mercury discussed. There is ample published research associating mercury as a cause of mast cell mediator release, including this study.