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Covid INFECTS the brain in multiple areas: one of the main receptors that virus uses to bind and replicate is ACE2: seen here: ACE2 is all over the brain itself in multiple regions: One of highest levels found in amygdala, which is responsible for fear processing and agression: 
Seen here: how virus attaches to cells via ACE2 receptors allowing for replication in cells
If you look at the areas of brain with highest ACE2 levels they correlate to the symptoms and behaviour changes from infection: because it's infecting the brain itself twitter.com/i/web/status/1…
That's there's much aggression and violence everywhere now
Virus also uses neuropilin (NRP1) receptors to gain entry: neuropillin is used in pain regulation and is found all over the central nervous system and crucially also in the olfactory bulb in the brain:
It is believed that this is the one of the main reasons why so many people have mild and or asymptomatic acute infections:
sciencedaily.com/releases/2020/…
sciencedaily.com/releases/2020/…
'SARS-CoV-2, the virus that causes COVID-19, can relieve pain, according to a new study by University of Arizona Health Sciences researchers.
The finding may explain why nearly half of people who get COVID-19 experience few or no symptoms, even though they are able to spread..
The finding may explain why nearly half of people who get COVID-19 experience few or no symptoms, even though they are able to spread..
..the disease, according to the study's corresponding author Rajesh Khanna, PhD, a professor in the College of Medicine -- Tucson's Department of Pharmacology.
"It made a lot of sense to me that perhaps the reason for the unrelenting spread of COVID-19 is that in the early ..
"It made a lot of sense to me that perhaps the reason for the unrelenting spread of COVID-19 is that in the early ..
..stages, you're walking around all fine as if nothing is wrong because your pain has been suppressed," said Dr. Khanna. "You have the virus, but you don't feel bad because you pain is gone. If we can prove that this pain relief is what is causing COVID-19..
..to spread further, that's of enormous value."
The paper, "SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia," will be published in PAIN, the journal of the International Association for the Study of Pain.'
The paper, "SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia," will be published in PAIN, the journal of the International Association for the Study of Pain.'
So basically the virus numbs to the pain that people should be feeling while it replicates ever more into cells, including up in the brain.
'NRP1 is abundantly expressed in the respiratory and olfactory epithelium, with highest expression in endothelial and epithelial cells. Daly et al. found that the furin-cleaved S1 fragment of the spike protein binds directly to cell surface NRP1 and blocking this interaction.. twitter.com/i/web/status/1…
...with a small-molecule inhibitor or monoclonal antibodies reduced viral infection in cell culture.
science.org/doi/10.1126/sc…
science.org/doi/10.1126/sc…
OLFACTORY bulb seen here: this has the NRP1 pain receptors virus infects all over it: this area of the brain is implicated in smell, taste and memory:
Olfactory and Alzhiemer's dementia: shows the regons in brain linked by olfactory which we know the virus infects through pain receptors thus blocking the signalling from pain: THIS IS THE MUCH RAVED ABOUT MILDNESS BY THE WAY!
Nothing brings sadness to me more than someone saying they had or have 'mild' Covid, because I know there's no such thing: all it means is virus has found a way in with minimal or no symptoms by infecting and disabling your defences: it will destroy regardless
This is why you see the so called happy hypoxia and all the bizarre 'they should be seriously ill' biomarkers: they have been anesthetized to not feel painand the immune system has been suppressed by the virus:
It might sound counterintuitive but you need to feel ill when infected, because that's a sign the immune system is working: a lot of the illness felt during infection is due to the immune system fighting infection: if you don't feel that then it's going unchecked
It means your immune system is allowing it to go everywhere and do what it what it wants: conversely there is the exact opposite effect where the virus after going unchecked then sparks a huge immune response in which the immune system attacks itself:
that's the cytokine storms, PIMs, the new onset autoimmune disease sparked after acute infection etc etc
in summary: virus infects the brain and central nervous system in key areas and can do why people feel just fine: the damage caused can easily go unnoticed and then one day boom 'suddenly deaded' throw em on the heap with the millions of other 'mystery deaths'
Might sound extreme, but given the biology of this disease, I personally have written off any hope for the next generations: the kids who have been mass infected as this point and continue to be: they're not going to withstand this as they go into adulthood: that's why teens… twitter.com/i/web/status/1…
Anybody who describes this virus as mild when it infects the brain itself and the CNS and THE IMMUNE SYSTEM and depletes it is scum of the lowest order and any description of this virus as mild has no place: objectively no place in any serious discussion, let alone journal… twitter.com/i/web/status/1…
Covid is supposed to be a respiratory virus, but the respiratory part is not the biggest aspect: it's the immune depletion and neuro disease and multi organ diseases it causes and while the world's leader and corporations like to pretend Covid is over: that hasn't made this go… twitter.com/i/web/status/1…
is important to understand that the amyloid plaques, found to be caused by Sars 2 viral proteins, which are the hallmarks of Alzheimers, are also implicated in many neurodegenerative diseases:
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