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May 30 9 tweets 2 min read Twitter logo Read on Twitter
In this one, both an elevated lipid accumulation product (LAP) and an visceral adiposity index (VAI), were associated with an increased risk for early-onset type 2 diabetes among young Chinese adults.
- The lipid accumulation product (LAP) is a marker designed to measure cardiovascular disease risk factors that integrates waist circumference, an indicator of abdominal obesity, and triglyceride levels.
* LAP index (females)=TG (mmol/L)×(WC [cm]−58)

* LAP index (males)=TG (mmol/L)×(WC [cm]−65)
- The visceral adiposity index (VAI) is an indirect indicator of fat distribution and function.
* VAI = (WC/(39.68 + 1.88 × BMI)) × (TG/1.03) × (1.31/HDL) for men.

* VAI = (WC/(36.58 + 1.89 × BMI)) × (TG/0.81) × (1.52/HDL) for women.
- Patients in the 4th quartile of LAP and VAI had 2.257 and 4.705 times higher risk of type 2 diabetes before age 40, compared to those in the 1st quartile, respectively.
- A tenfold increase in LAP was associated with a decrease in type 2 diabetes onset age of 12.862 years in males and 6.507 years in females.
- A tenfold increase in VAI was associated with a decrease in type 2 diabetes onset age of 15.222 years in males and 12.511 years in females.
Comparison of lipid accumulation product and visceral adiposity index with traditional obesity indices in early-onset type 2 diabetes prediction: a cross-sectional study (open access)

doi.org/10.1186/s13098…

#Obesity #MetabolicSyndrome #InsulinResistance #Diabetes

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