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Ashley Love Sumrall, MD, FACP

@AshleySumrallMD

Jun 5

@adrienne_boire

Quick recap of outstanding talk by @adrienne_boire 👉🏻 we MUST open our minds to seek out LMD. Do the LPs, send the csf (esp CTCs), look for tx options/ trials. #btsm #asco23 1/

Imaging is 1st step. But "all that glitters isn"t gold." Esp consider this for pts on immunotx. Sens of MRI 71-100%. Slide 3 w broad ddx #asco23 2/

What csf studies? 3/

Read 5 tweets

Ashley Love Sumrall, MD, FACP

@AshleySumrallMD

Jun 4

And TODAY is that day! #btsm #asco23 12/

Today's announcement of data from #Indigo is a HUGE milestone for these pts & their families. #IDH #btsm 👉🏻 nejm.org/doi/full/10.10… 13/

Pts w grade 2 tumors & no tx aside from surgery, took placebo or po #vorasidenib. mPFS: 27.7 mo vs placebo 11.1 mo. Time to next intervention was longer in vorasidenib arm. (HR, 0.26; 95% CI, 0.15 to 0.43; P<0.001). 14/

Read 4 tweets

Ashley Love Sumrall, MD, FACP

@AshleySumrallMD

Jun 4

@ASCO

In light of today's plenary @ASCO #asco23 👀
Grade 2 gliomas👉🏻 a tutorial. #btsm
Considered a low-grade glioma, but also considered to be a terminal illness. How? These tumors are incurable and affect adults, teens, & children. #asco23 1/

They are insidious and will sometimes stay quiet for years. They may be oligodendrogliomas (aka lazy tumors) or the more aggressive astrocytomas. I often tell my pts that grade 2 tumors have 2 goals in life: grow BIGGER and/ or change to a more aggressive form. 2/

On the imaging, they often do not enhance, and can sometimes be missed. The key is to look at T2 and flair images. These pts must be monitored closely because the tumors can become motivated to change at any time. 3/

Read 11 tweets

Ashley Love Sumrall, MD, FACP

@AshleySumrallMD

Nov 25, 2019

@asco

🚨Tweetorial: NTRK 101 🚨Given the data discussed at @asco #ASCO2019 & @sno #SNO2019 on #NTRK fusions in primary brain tumors & brain mets, I thought we could review the background of these fusions, how to find them, and then look at potential options for tx. #btsm

@carisls

<Disclaimer: I’m a speaker for Bayer (larotrectinib) and a subI for the STARTRK trial using entrectinib. I also have ongoing research work w @carisls > I’m keeping this as bias-free as possible though. Ok, next...

With the increase in tumor profiling & expanded options using #RNAseq, it seems like it is getting easier to find an #NTRK fusion. It can easily feel like Christmas when you do! 🎄 Just remember that an #NTRK MUTATION is not 🚫 fusion. They aren’t = & treatments aren’t the same.

Read 26 tweets

Ashley Love Sumrall, MD, FACP

@AshleySumrallMD

Sep 27, 2019

@ASCO

🚨Advocacy 201: 🚨Getting personal with your members of Congress! @ASCO #ASCOadvocacysummit

If you mastered my advocacy 101 tweetorial, what’s next? Get to know your leaders & their teams via face-to-face meetings. #ASCOadvocacysummit

@asco

Are you planning a visit with a group like @asco? If so, follow their instructions. Most groups dispatch staff to go with you to navigate the schedule & locations. Going on your own? Keep reading. It’s easy!

Read 26 tweets

Ashley Love Sumrall, MD, FACP

@AshleySumrallMD

Sep 26, 2019

@ASCO

🚨Tweetorial 🚨Advocacy 101: how to get involved in sharing your message about pts with cancer 🎗with lawmakers 🇺🇸 @ASCO #ASCOadvocacysummit

@asco

Advocacy101: I’m a busy oncology Physician/ Nurse/ Pharmacist/ APP/ Patient/ Caregiver/ Etc. I want to express my opinion, but where do I start? @asco #ASCOadvocacysummit b