Researchers have analyzed nonhuman #PrimateGenomes from more than 230 species. The results show how these data can help us learn about both nonhuman primate biology and our own health.
Learn more in a new special issue of Science: scim.ag/2Sq (THREAD 🧵)
A new study in Science presents whole-genome data from 233 primate species representing 86% of the primate genera and all 16 families. scim.ag/2Sr#PrimateGenomes
Despite the importance of nonhuman primates, reference genomes have been sequenced in <10% of species.
A new Science study presents high-quality reference genomes for 27 primate species, adding to available resources. scim.ag/2Ss#PrimateGenomes
By accounting for incomplete lineage sorting across primates, researchers in a new Science study were able to produce a primate phylogeny that agrees with fossil estimates, unlike past attempts. scim.ag/2St#PrimateGenomes
The gray snub-nosed monkey is derived from hybridization between the golden snub-nosed monkey and the ancestor of two extant Rhinopithecus species—a notable example of hybrid speciation in primates, a new Science study finds. scim.ag/2Su#PrimateGenomes
Cold environments promoted the social evolution of Asian colobine primates in a stepwise manner, according to a new Science study. scim.ag/2Sv#PrimateGenomes
Using whole-genome sequencing, researchers in a new Science study reveal the evolutionary history of overlapping baboon species, finding evidence of repeated admixture. scim.ag/2Sw#PrimateGenomes
In a new Science study, researchers present PrimateAI-3D, a deep-learning model trained on millions of benign primate variants. scim.ag/2Sx#PrimateGenomes
Using the deep-learning model PrimateAI-3D, researchers in a new Science study help uncover the role played by rare penetrant variants in common human diseases and complex traits. scim.ag/2Sy#PrimateGenomes
In @ScienceAdvances, researchers investigate the evolutionary landscape of lineage-specific accelerated regions (LinARs) across 49 primate species.
The results broaden knowledge of the functional roles of LinARs in primate evolution. scim.ag/2Sz#PrimateGenomes
@ScienceAdvances By comparing reference genomes of 12 macaque species that together cover all the known macaque groups, researchers in @ScienceAdvances have uncovered an ancient hybrid origin of a macaque lineage. scim.ag/2SA#PrimateGenomes
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A new special issue of Science considers recent developments in monitoring, health effects, and policy dealing with #AirPollution. (THREAD 🧵) scim.ag/7Np
Two of the most popular mapping methods, mobile monitoring and low-cost sensor networks, have complementary strengths in measuring urban air quality, argues a new #ScienceReview. #AirPollution scim.ag/7PU
A #ScienceReview looks at the new air quality guidelines from @WHO and related challenges in improving air quality and health. #AirPollution scim.ag/7PV
Scientists have made several advances in the design of a class of #HIV vaccines that could offer broad protection against the virus, according to four new research papers published in Science, @ScienceTM, and @SciImmunology. (THREAD 🧵) scim.ag/6ZB
Leveraging cryo-electron microscopy, researchers in Science show a new approach that successfully primed and boosted quantities of B cells that secrete precursors to BG18—an anti-#HIV broadly neutralizing antibody—in a group of eight rhesus macaques. scim.ag/6YM
In a preclinical model, researchers in Science used sequential immunization to demonstrate the effective boosting of primed broadly neutralizing antibody precursors by two second-stage immunogens. scim.ag/6YN
In 2016, Science published the structure of the #NuclearPoreComplex—the sole gateway for macromolecules to enter or exit the nucleus.
A new special issue builds on that work, presenting the structure in unprecedented detail. fcld.ly/jfvwxfe (THREAD) 🧵
A composite structure of the cytoplasmic face of the human #NuclearPoreComplex provides a rich foundation for elucidating the molecular basis of #mRNA export and nucleoporin diseases, according to a new Science study. fcld.ly/3v012d9
In a new Science study, researchers present a near-atomic composite structure of the human #NuclearPoreComplex’s ~64-megadalton symmetric core. The findings provide a basis for future functional studies. fcld.ly/wgoa4cj
The human body is home to a variety of microbiomes.
A new special issue of Science looks at our current understanding of these microbial communities, their effects on human health, and what remains to be discovered. fcld.ly/ny68b06 (THREAD) 🧵 #TheSystemicMicrobiome
Oral microbiota form distinct biofilms in different regions of the mouth that protect host tissues. When these biofilms become unbalanced, they may contribute to various diseases, including cancer and #Alzheimers.
2021 has been a rich year in science, with a bounty of discoveries about biology and medicine, human prehistory, and the physical world.
Now, we want to know which one you consider this year’s top breakthrough. (THREAD) 🧵
Starting today, you can cast your vote in this thread for your favorite #BOTY in the three categories below. The winners will enter a final contest that runs 6–13 December. On 17 December, the People's Choice winner will be revealed. 🏆
If you would like to learn more about this year’s People’s Choice candidates, follow this thread after the polls for a short description of each, or read more here: fcld.ly/mwibvax
In preparation for #ShutDownSTEM tomorrow, 10 June, Science has made the following articles available without subscription or registration to help facilitate discussion.
"As more organizations and industries adopt digital tools to identify risk and allocate resources, the automation of racial discrimination is a growing concern."
In New York City, Latino and black people have been twice as likely to die from #COVID19 as white people. Research shows that this current pandemic is not atypical in hitting poor and marginalized communities harder. @NewsfromSciencefcld.ly/2ubp78q