Warwick 2021 registry: Asystole 51%, VF 22% - median EMS response time 7.4 mins. 57.5% declared dead on scene. admitted to hospital with ROSC 24.8% and 30-day survival 8.5% warwick.ac.uk/fac/sci/med/re…#UKECPR23
@tamishtah Paramedic 2(2018) study of adrenaline vs. placebo: but lets look at it for times. 999 arrival 6.6 mins, 30-day survival 3.2% (intervention) vs. 2.4% (control) nejm.org/doi/full/10.10…
What about international data ? U.K. looks abysmal in comparison to Norway #UKECPR23@tamishtah
#prolonged cardiac arrest. What does the critical care team have to offer? Bear in mind; relative exposure to cardiac arrest - even for more experienced paramedics >17 cardiac arrests in 3 years. 🤔 #UKECPR23@tamishtah
Dr James Raitt starting with #airway management for #OOHCA. SGA is the way to go but Euro resus council ERC target > 95% success in 2 or fewer attemptts for tracheal intubation for exert. Unpublished data from air ambulances in UK, most air amb meets this. #UKECPR23
#SPEAR programme. Very interesting area. Quantifying the effects and ability to titration Rx. #UKECPR23@tamishtah
and #REBOA ? -the recent trial disappointing but more ongoing data and trial coming in.
- how about #headup#CPR? and CABARET - impedance threshold device?
- what about all 'bundled' together?
Next post #ROSC care - 1. airway Mx - drug induced TI vs. cold intubation #UKECPR23
In summary -
there is #scope for improvement
- bystander CPR & early defibrillation
- the more you do it , the more you get better thus need more dedicated teams
- look out for novel intervention (?haemodynamic guided CPR) #UKECPR23
Dr James Raitt message : want to call cardiology services and other hospital specialists to share knowledge together and share vision. Especially #access to #cathlab.
But what #kind of #registries ? - Patient, Specialty, Device ? e.g., Abiomed Imeplla registry data. Regulatory process is different - FDA normally requires RCT. Abiomed registry data was compelling , resulting in +++ impella uptake in USA. #UKECPR23
Mariangela PELLEGRINI
Uppsala- Sweden
"Do we Need a biological definition of ARDS"
- Berlin definition has NO Diffuse alveolar damage .
- the Berlin defn does not capture well
Frohlich - different definitions specificity of 0.63, 0.42, 0.31 even! #ventilation#ards#LIVES2022
ARDS - new definition or phenotypes by @GicoBellani refreshing with Kigali definition of ARDS - useful not just low resource but during pandemic in supposedly high income settings and only draw back is no PEEp requirement #ards#ventilation#LIVES2022@ESICM
@GicoBellani@ESICM Resolved versus confirmed ARDS
- prospectively applying Berlin definition did work but if ya wait 24 hrs and re-measure P/F ratio, you end up stratifying much better.
- Better separation of groups