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Paul Cook Profile picture CK Profile picture 2 subscribed
Jan 11, 2021 7 tweets 4 min read
Thread

Life expectancy over a 300 year time span

1800 to 2100

(IMO I believe millennials who looks after themself now will now live beyond 150 years old due to health care advancements over the following decades🤷🏼‍♂️)

Call me crazy 🤪 1800 to 1890

From 43yrs to 50yrs (16% incr)
Jan 9, 2021 6 tweets 4 min read
#DDDD

I think the fact that MRx0518 is showing massive near term promise in cancer, yet 4D continue to focus on Parkinson's Disease shows me how excited and effective they believe MRx0029 may be for Parkinson's
(Market expected to reach $8.3bn by 2026)

medgadget.com/2020/02/parkin… Image #DDDD $LBPS

After discussing MRx0029 in the text, the author from 4D heavily alludes to bringing in a partner... Image
Jan 7, 2021 19 tweets 12 min read
#RENE

Totally agree $CDAK are around 18months further advanced in the development of Exosomes (delivery vehicle)

#RENE Mcap= £60m
$CDAK MCap= $591m

3 Companies evaluating RENE's platform

Currently snowed under with demand off other companies for Proof of Concept trials ImageImage #RENE

Are exosomes going to play a big role in future cell and gene delivery?

Aug 26, 2020 10 tweets 6 min read
#DDDD 💊

Today 4D announce phenomenal trial results for the combination of @Merck's KEYTRUDA with MRx0518 in Lung and Kidney Cancer💥🚨 #DDDD💊

A staggering 42% achieved clinical benefit in a population that had exhausted all other methods of disease/cancer treatment

For a population which has been resistant to all other lines of therapies, this is hugely encouraging... if they can treat the most resistant...
Jul 23, 2020 96 tweets 56 min read
#DDDD💊

Why I believe @4dpharmaplc are on the cusp of a multi hundred million pound licencing deal for IBD and IBS?

#DDDD💊

Great Video 'Our Approach' highlighting @4dpharmaplc world leading innovative concept

Harnessing the bodies own Microbiome (Gut Bacteria) to solve genetic imbalances and malfunctions commonly referred to as diseases

4dpharmaplc.com/en/newsroom/vi…
Jul 23, 2020 5 tweets 4 min read
#DDDD💊

Why I believe @4dpharmaplc are on the cusp of a multi hundred million pound licencing deal for IBD and IBS? #DDDD💊

Phase 1 data for @4dpharmaplc Blautix's treatment of IBS highlights significant efficacy

-82% Improvement in a reduction of symptoms
-More diverse stable gut bacteria

4dpharmaplc.com/application/fi… ImageImage
Jul 16, 2020 31 tweets 17 min read
#MXCT

MaxCyte is a cell engineering platform, which uses non viral mRNA for drug development in a wide range of diseases including
-Cancer
-Auto Immune Diseases

11 Commercial Licencing deals with over
-$800m in Milestone Payments Image #MXCT

MaxCyte is based on their patented novel drug development approach which is Flow Electroporation

Flow Electroporation is reprogramming of Human T-Cells

What this means is they have a machine that can modify any human/patients cells in order to target a specific problem Image
May 4, 2020 51 tweets 37 min read
I have substantially bought #DDDD today

I have done extensive research into #COVID19 treatments companies listed on AIM over the weekend (Around 30 HOURS❗❗) and came to the conclusions DDDD is the drug which is most likely to have great efficacy and safety data 💥💥💥 #DDDD

The Microbiome Therapeutics company focused on using an innovative solutions for treatment in unmet 21st century ailments

Areas of focus

-Vaccines
-Oncology (Cancer)
-Respiratory illnesses inc
---SARS-CoV-2 #COVID19
-Irritable Bowel Syndrome
-Central Nervous System