I just finished a great book: "Why Greatness Cannot Be Planned: The Myth of the Objective". It is a book about discovery, curiosity and novelty written by a pair of computer scientists. a THREAD with some polls... (1/n) link.springer.com/content/pdf/10… Let me start with some polls about goals/objective functions over which we maximize at different career goals. Allow me some humor and some seriousness. (2/n)

(TWEETORIAL - THREAD)

Psyched to share new #mathonco #RadOnc results. New @medrxivpreprint :

Optimizing Clinical Outcome and Toxicity in Lung Cancer Using a Genomic Marker of Radiosensitivity

medrxiv.org/content/10.110…

(1/7) Building on the results from our previous paper showing how to derive the Genomically Adjusted Radiation Dose, we ask what else we can learn about our patient heterogeneity related to radiation dosing. thelancet.com/journals/lanon… (2/7)

Controlling the speed and trajectory of evolution with counterdiabatic driving -- a TWEETORIAL 0/n #evolution #mathonco #mathevo #physics #quantumcomputing biorxiv.org/content/10.110… #Evolution is the most fundamental biological *mechanism - and drives change over time across all the kingdoms of life. We are getting better and better at *predicting* its outcomes, and *harnessing it* (directed evolution), but we haven't previously had any *control* over it 1/n

(1/n) Excited that final version of work led by @D4N__ studying evolutionary repeatability and collateral sensitivity is out. #mathevo #clecliniccancer nature.com/articles/s4146… @CCLRI @NatureComms @CWRUSOM (2/n) This collab between @CompSciOxford @CCLRI @CWRUSOM & @MoffittPSOC is an extension of @D4N__ ‘s initial theory paper that proposed ‘steering evolution’ as a method of extending the use of existing drugs to control infection. #AntibioticResistance journals.plos.org/ploscompbiol/a…