Jake Scott Profile picture
@CWRUSOM @OxUniMaths @ClevelandClinic Sarcoma #radonc #mathonco #mathevo @NavalAcademy submarine #veteran tweets=mine he/him TEDMED https://t.co/yBCRcx52pW
Jan 14, 2020 7 tweets 4 min read

Psyched to share new #mathonco #RadOnc results. New @medrxivpreprint :

Optimizing Clinical Outcome and Toxicity in Lung Cancer Using a Genomic Marker of Radiosensitivity


(1/7) Building on the results from our previous paper showing how to derive the Genomically Adjusted Radiation Dose, we ask what else we can learn about our patient heterogeneity related to radiation dosing. thelancet.com/journals/lanon… (2/7) ImageImage
Dec 6, 2019 13 tweets 9 min read
Controlling the speed and trajectory of evolution with counterdiabatic driving -- a TWEETORIAL 0/n #evolution #mathonco #mathevo #physics #quantumcomputing biorxiv.org/content/10.110… #Evolution is the most fundamental biological *mechanism - and drives change over time across all the kingdoms of life. We are getting better and better at *predicting* its outcomes, and *harnessing it* (directed evolution), but we haven't previously had any *control* over it 1/n
Jan 18, 2019 11 tweets 11 min read
(1/n) Excited that final version of work led by @D4N__ studying evolutionary repeatability and collateral sensitivity is out. #mathevo #clecliniccancer nature.com/articles/s4146… @CCLRI @NatureComms @CWRUSOM (2/n) This collab between @CompSciOxford @CCLRI @CWRUSOM & @MoffittPSOC is an extension of @D4N__ ‘s initial theory paper that proposed ‘steering evolution’ as a method of extending the use of existing drugs to control infection. #AntibioticResistance journals.plos.org/ploscompbiol/a…