And here we go.
thelancet.com/journals/lanin… 1/ Key: "The observed pulmonary vascular dilation might be due to relative failure of normal, physiological hypoxic pulmonary vasoconstriction in the setting of overactivation of a regional vasodilatation cascade as part of a dysfunctional and diffuse inflammatory process." 2/

I'd like to point out that while the resolution of a #chronicillness was striking, what is more striking is the rapid descent into Wernicke's in a hospitalized 90 yo woman - a descent so striking that she went into respiratory distress necessitating a #ventilator. 1/

https://twitter.com/ChanatLucine/status/1255900635825713152

Upon giving #IVthiamine per a #wernickesprotocol at 200mg 3X p/d she woke up, after just 2 days of thiamine treatment, and the ventilator was removed. What could this tell us about the use of thiamine in #COVID19? Perhaps the cluster symptoms we see are really just a variation 2/

I want to talk about 2 papers that highlight the role of mitochondria in what are likely the progression of symptoms assoc with #COVID19. Note these papers are not about #covid but highlight important pathways. 1/ 1st paper - Intracellular ATP is req. 4 #mitochondrial #apoptotic pathways rat #cardiac #myocytes ncbi.nlm.nih.gov/pubmed/12909326 2/