David T. Rubin, MD Profile picture
Professor and Chief of GI, The University of Chicago Medicine. I specialize in and advocate for the care of IBD patients. My tweets are my own. (he/him)
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Jul 30, 2021 6 tweets 4 min read
Here is my lecture for patients about #COVID19 and vaccination with specifics about #IBD.
I recorded this July 21, so please keep that in mind related to the subsequent mask update from @CDCgov.

But my explanations and comments are still on point.

bcove.video/3l6clDX Image Take time to listen - it's 33 minutes, the #IBD part starts at min 12.
I explain variants and what they mean, and how dangerous delta is.
I review the consistent data that show vaccines work in patients with IBD and are SAFE in patients with IBD.
2/5 Image
Apr 17, 2021 18 tweets 7 min read
A brief Tweetorial to clarify the NYT article from 15 April and further explain/clarify the Kennedy paper (that is in press in Gut).
I've previously commented about the Kennedy paper in this forum, but it bears repeating and further explanation now.
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gut.bmj.com/content/70/5/8… The recent NYT article highlights the important issues/concerns of those who are immune compromised due to innate disorders, chemotherapy, or some treatments.
It is important to emphasize the ongoing work and need for good research about #COVID19 and vaccines.
However...
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Dec 2, 2020 20 tweets 9 min read
Here are my thoughts and a few updates about #SARSCoV2 vaccines, and also about implications for our #IBD patients.
A tweetorial in 20 parts. 1) Development of multiple #SARSCoV2 vaccines in the timeframe we have seen is a monumental scientific achievement.
Necessity literally bred invention.
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Apr 7, 2020 21 tweets 7 min read
I've created a thread that summarizes the statements from the #IOIBD global expert panel about management of #IBD during #COVID19. This is because the meeting summary of _appropriateness_ statements is being a bit misunderstood.
doi.org/10.1053/j.gast…
Read on ⬇️⬇️
1/ First, a disclaimer! The statements by this expert panel are not meant to replace conversations between a patient and their healthcare providers, nor are they set in stone. As we learn more, there will be modifications provided.
▶️IOIBD is holding weekly calls about #COVID19.
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Mar 28, 2020 16 tweets 7 min read
Improvements in testing for #SARSCoV2 and #COVID19 and how they will transform what we are doing (a Tweetorial):
1) FASTER VIRAL TESTS for SARSCoV2 (the virus). Several companies have adapted existing point-of-care tests that can provide results in MINUTES.
Read on ⬇️⬇️⬇️
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Faster tests for #SARSCoV2 may be less sensitive or specific for detecting the virus but we can figure this out.
Less sensitive means more false negative results (you actually have the virus, but the result says you don't).
Less specific means more false positive results.
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Mar 16, 2020 5 tweets 4 min read
Update 15 March #COVID19 and #IBD. Due to the active communication of colleagues around the globe, we are now aware of several worldwide cases of #COVID19 in patients who have IBD, including one child.
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Reports that the #IBD adults are in Italy, Austria and US (NJ), the child is in Madrid, Spain.
The child has #Crohns receives Humira + 6MP. She presented with fever and cough, was not hospitalized, and is doing well.
I do not have more details on the adults yet. #COVID19
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Mar 9, 2020 6 tweets 7 min read
Brief update on #COVID19 for inflammatory bowel disease (#IBD) patients as of 9 March 2020.
See the updated #IOIBD COVID19 recommendations on the ioibd.org website.
1/ The #IOIBD site now includes this statement: "It is prudent that IBD patients on immunosuppressants and/or biologics limit unnecessary travel and large gatherings." (and spells out these therapies) However, please know that we still recommend staying on treatment. Read on. 🔽
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Feb 27, 2020 9 tweets 6 min read
A Tweetorial on #coronavirus (and #IBD):
Coronaviruses are a family of viruses that can cause illness from the common cold to more severe diseases. The novel strain of #coronavirus named #SARSCoV2 was first detected in Wuhan, China and causes coronavirus disease #COVID19. 1/ How is #coronavirus transmitted?
Via respiratory droplets produced when an infected person sneezes or coughs and can infect people in close contact (within 6 feet). Touching contaminated surfaces before touching your eyes/nose/mouth might also lead to infection. 2/
Dec 15, 2019 5 tweets 4 min read
We are developing and studying biosensors as tools to predict #IBD activity (a thread in 5 parts).
In press: we show the correlation between standard instruments of PAIN, QUALITY of LIFE and SLEEP QUALITY and simplified Visual Analog Scales. #RubinLab 1/ academic.oup.com/crohnscolitis3… ImageImage We demonstrated high correlation between daily single "click" and "swipe" rating by a patient of their global health and sleep quality and the standardized validated and more cumbersome survey instruments that require recall of prior days/weeks. #RubinLab @UChicagoIBD 2/