. There are several theories & models, such as insulin resistance, or cardiometabolic reserve, inflammation or other comorbidities, but mystery remains.
Now two case reports from Italy of #COVID19 autopsies finds clear signs of fat embolism within lung tissue, which could go a long way to explaining several unique features (radiographic, coagulopathic, neurologic) found in severe cases of #COVID19. nature.com/articles/s4136…
Jun 8, 2020 • 11 tweets • 6 min read
1. Why do some #COVID19 cases have severe outcomes while others are mild? Many of the comorbidities associated with poor outcomes are also associated with #obesity. A new paper looks even deeper to find an underlying link ==> chronic inflammation nature.com/articles/s4136…2. The authors of this paper are familiar with how one size does not fit all with obesity. @DrSharma established the Edmonton Obesity Staging System to help characterize obesity beyond size alone to address physical, mental, and functional health. drsharma.ca/wp-content/upl…
