Janosch Profile picture
Microbiologist by training | Scientist at heart | #Scicomm enthusiast | Work @BioPharmaCL_GER | Trainer @NaWik | He/him | 1 out of 4 in the pack
May 6, 2021 9 tweets 5 min read
"#AstraZeneca, we have a problem"

New #preprint from Lena Krutzke and Stefan Kochanek et. al. @uni_ulm and @UniklinikUlm on @researchsquare

"Process-related impurities in the ChAdOx1 nCov-19 vaccine"

Why is this a problem? A short thread (1/8) 👇
researchsquare.com/article/rs-477… "The intramuscular injection of proteins that are not part of the active principle of the #vaccine itself might have effects at different levels"

That`s why removal of impurities (e.g. host-cell proteins) is critical for #therapeutics and strictly regulated