Michaël Laurent иди нахуй путин Profile picture
Geriatrician MD PhD, passionate about osteoporosis, rare/genetic bone diseases, sarcopenia, orthogeriatrics. Imelda & UZ Leuven. Belgian Bone Club. Now COVID-19
Dec 30, 2022 42 tweets 29 min read
As the year ends, it's time once again to discuss some of the best clinical papers in the 🦴 #bone field in 2022!

A long 🧵
@Sandroppa @ECTS_science @larsfolkestad Nr. 1: Supplemental #VitaminD and Incident #Fractures in Midlife and Older Adults @NEJM

No effect in the VITAL trial although confidence intervals do not exclude meaningful reduction in patients on osteoporosis meds or with fracture history

nejm.org/doi/full/10.10…
May 14, 2021 15 tweets 12 min read
Proud 🤩 to present our preprint on the use of #CO2 monitors in hospital: background, pilot data and protocol for an RCT.
A #COVID19 🧵 @trishgreenhalgh @mjb302 While Belgium is about to become one of the first countries to mandate #CO2monitors in bars, no evidence supports their use, which is particularly problematic in clinical medicine #EBM. How are CO2 levels in hospitals? What does the literature say? @HuffmanLabDU @j_g_allen
Dec 20, 2020 24 tweets 25 min read
With 2020 almost over, it's time again to look back at some of the BEST in the #bone field: 🔝20 papers (+extras).

Happy to hear your input! Disclosure: fully subjective ranking!
@ASBMR @AcademyEcts @Osteoporosis_NL @osteoporosisNI @mmse30 @NatalieASims #1 Atypical Femoral fractures @NEJM (Black DM et al.)
Risk reduces within months of @Bisphosphonate1 discontinuation. Benefit>risk in any group but less so in Asians and women <65yr
nejm.org/doi/10.1056/NE…
Aug 30, 2020 7 tweets 4 min read
Every doctor carries along her/his own little graveyard. Inevitably, we make mistakes. People die, or become disabled. You never forget those patients. 1/n In my first year of training there was a 20yo woman with stage IV lymphoma (DLBCL). She was clinically fine but I overlooked her creatinin which showed severe CKD from diuretics. 1w later she came in with heart block from betablocker overdose and died. 2/n