45 F w/Hx of hypertensive nephropathy complicated by ESDR s/p kidney transplant 7 mo ago, on tacrolimus & MMF. CMV D+R-, who after completing prophylaxis w/ valganciclovir for 6mo is admitted with 3 wks of watery diarrhea
2/3 Colonoscopy findings consistent with CMV colitis. Initial CMV DNAemia 800 IU/mL. Patient’s immunosuppressive regimen is reduced, and she is treated with ganciclovir 5 mg/kg IV every 12 hours.
44 year old male, HIV (+), non adherent to antiretroviral therapy (CD4 120) presents for evaluation of this lesion:
🤔 The most likely microorganism responsible for this finding is:
37 y/o F PMHx of lupus nephritis complicated by ESRD s/p living-donor kidney transplant 5 months ago, who presents with 3 days Hx of dysuria, hematuria, pelvic pain and subjective fever
2/5 She denies recent lupus flares. Patient is taking tacrolimus, mycophenolate, prednisone and TMP-SMX. Vaccinated against COVID-19x3. No sexually active for the past year. PreTransplant HIV,CMV,HepBC, adenovirus, Toxo and trypanosoma serologies (-) for both patient and donor.
39y/M with no PMH, presents to the ED for evaluation of fatigue, anorexia, and diarrhea of 3 weeks duration. ROS is positive for weight loss, night sweats and an intermittent maculopapular rash located on his chest
2/5 Patient denies recent travel, sick contacts. He works as a bus driver. Sexually active with cis male partners, no condom use, takes PrEP occasionally. Hx of treated syphilis, last HIV and QuantiFERON-TB 6 months ago negative
