Erik Nelson Profile picture
PhD Candidate @CMM_JHU @HopkinsMedicine @LieberInstitute, studying transcriptomics and activity-regulated genes in the context of human psychiatric disorders
Dec 2, 2022 10 tweets 10 min read
In my 1st tweetorial, I’m happy to share our preprint—my first, first author manuscript! We used @10xGenomics single-nucleus RNA-seq in a mouse model of electroconvulsive seizures (ECS) to assess activity-regulated gene expression in hippocampal #neurons. biorxiv.org/content/10.110… Activity-regulated gene expression patterns in the #hippocampus regulate #plasticity, #learning, and #memory, and are linked to risk and treatment response for neuropsychiatric disorders. However, the cell type-specificity of these patterns is still not well characterized.