PhD Candidate @CMM_JHU @HopkinsMedicine @LieberInstitute, studying transcriptomics and activity-regulated genes in the context of human psychiatric disorders
Dec 2, 2022 • 10 tweets • 10 min read
In my 1st tweetorial, I’m happy to share our preprint—my first, first author manuscript! We used @10xGenomics single-nucleus RNA-seq in a mouse model of electroconvulsive seizures (ECS) to assess activity-regulated gene expression in hippocampal #neurons. biorxiv.org/content/10.110…
Activity-regulated gene expression patterns in the #hippocampus regulate #plasticity, #learning, and #memory, and are linked to risk and treatment response for neuropsychiatric disorders. However, the cell type-specificity of these patterns is still not well characterized.