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https://twitter.com/vinodscaria/status/1384375736643952640Mutations in B.1.1.7 and B.1.617, both well established, lineages would have been fixed for some benefit. For nature to choose *not* to fix them in B.1.618 implies some benefit of losing them. Of course, protein allostery incredibly hard to predict a priori, but Occam's razor..
https://twitter.com/K_G_Andersen/status/1375292808278372358With little understanding of the level of underdetection, could be easily be a couple immunocompromised hosts + few transmissions. Or The 18907 V->F is in nsp14 and might impact Rdrp proofreading. All said, any claims on immune evasion/transmissibility are only hypotheses now
https://twitter.com/ScienceMagazine/status/1346849035563528195Wish the media brouhaha over waning immunity and antibody titers by immuno armchair experts could have been avoided. All that mental stress, public confusion, for what? Just let science do it's job. Please.