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Dr. Om Lakhani, MD, DNB (ENDO) Profile picture
Dr. Om Lakhani, MD, DNB (ENDO)
@omlakhani
Endocrinologist & Technocrinologist. The maker of DoctorGPT, Notes in Endocrinology, AlgoMed, EndoAI
2 subscribers
Aug 7, 2023 • 14 tweets • 2 min read
🧵 Twitter Thread: The Surprising Case of a 6-Year-Old with Diabetes Mellitus 1/ Hey Twitterverse! 🌟 Today, I want to share an intriguing case that highlights the importance of considering all possibilities when diagnosing diabetes in children. Meet a 6-year-old boy who presented with newly diagnosed diabetes mellitus. #Diabetes #MODY #Pediatrics
Jul 18, 2023 • 18 tweets • 2 min read
Oxytocin Deficiency in Patients with Diabetes Insipidus 🧪🩺 1/ Oxytocin deficiency in patients with diabetes insipidus (DI) has been investigated in a recent study published in The Lancet Diabetes & Endocrinology. Let's dive into the key findings and implications of this research!
May 17, 2023 • 10 tweets • 2 min read
MC Thomas in his article argues that Type 2 Diabetes should be renamed the "CARAMEL Disease" (A 🧵) What does CARAMEL stand for ?

CARAMEL stands for CArdiac, Renal, Adipo-Metabolic, Eye and Liver disease
May 16, 2023 • 5 tweets • 3 min read
Good morning everyone,

Happy to share that we have received research funding from the RSSDI for our Precision Medicine project called Diabetology.co.in.

#MedTwitter #EndoTwitter #Technocrinology Image Diabetology.co.in is India's first and only evidenced based precision medicine & personalized medicine platform for diabetes made for the doctors and by the doctors.
Apr 5, 2023 • 6 tweets • 1 min read
Q. What is Hemoglobin Glycation Index ? 1/5: 🩸 The Hemoglobin Glycation Index (HGI) compares a person’s actual HbA1c level to their predicted level based GMI (glucose management index) value from CGM
Apr 4, 2023 • 7 tweets • 1 min read
What is the Clarke error grid?

The Clarke Error Grid Analysis (EGA) is a tool developed in 1987 to assess the clinical accuracy of blood glucose meters by comparing their readings to reference values. The grid breaks down a scatterplot of a reference glucose meter and an evaluated glucose meter into five regions:
Jun 20, 2022 • 6 tweets • 2 min read
Initiating insulin (Tips from Approaches to Behaviour book by Roszler et al)

The patient breaks down and starts crying when she is advised to take insulin

How do you approach such a patient?

A thread 🧵

Contd... 1. You say:
"I see that this really upsets you.? "What bothers you the most?" (Identify.) Sue says she is afraid of the pain.

Contd...
Jun 18, 2022 • 5 tweets • 2 min read
Just to reiterate

The @ADA_DiabetesPro guidelines recommend Lifestyle measures plus pharmacotherapy as first-line therapy in patients newly diagnosed to have Type 2 Diabetes

The point being there should not be any delay in starting pharmacotherapy for type 2 dm

Contd.. Image The guidelines also clearly state that those presenting with catabolic symptoms at the time of first presented should be started on insulin which can then be stopped once the glucotoxicity is resolved

Contd... Image
Feb 15, 2022 • 12 tweets • 2 min read
Lesson 1 from the book "Noise" by Kahneman, Sibony et al

What is "Noise" in judgment?

A thread... Image To understand "Noise", we need to first understand "Recurrent decisions"

A recurrent decision is something that is made repeatedly on a day-to-day basis.

For example, an Endocrinologist making a decision on the treatment plan for a patient with Type 2 Diabetes
Jul 27, 2021 • 11 tweets • 3 min read
1. Any form of weight loss can lead to diabetes remission. (The right word to use here is remission and no reversal.) You DON'T NEED LOW CARB DIET for the same. The same can be achieved with any strategy which produces weight loss 2. Similar results can also be achieved with a balanced low-calorie diet, meal replacement (as shown in the DIRECT trial), bariatric surgery (as shown in several trials) and SGLT2i/GLP1 receptor agonist (as shown in several trials)
Jun 24, 2021 • 7 tweets • 2 min read
If Toto Wolff gives a contract to Russell instead of Bottas for 2022, and then Hamilton retires, what happens next? a) Ocon is already locked with Alpine till 2024

b) Lando is locked with McLaren

c) Leclerc and Sainz are unlikely to move out of Ferrari

d) If Max wins his maiden title with Red Bull, he is unlikely to leave the seat
Jun 24, 2021 • 13 tweets • 3 min read
Q1. Do statins reduce the risk of heart attack and stroke ?

"Statin therapy significantly reduces the incidence of major vascular events and vascular mortality in a wide range of people." "Reduction of LDL cholesterol using statin therapy reduces all-cause mortality by about one tenth for each 1 mmol/L (39 mg/dl) reduction in LDL cholesterol, principally reflecting a significant reduction in vascular mortality."

Ref: cttcollaboration.org/efficacy-web-p…
Jun 24, 2021 • 14 tweets • 4 min read
If you want to look about the use of Statins (Cholesterol lowering medications) to prevent heart attack and stroke, you don't need to look beyond the series of excellent meta-analysis conducted by the "Cholesterol Treatment Trialists' Collaboration"

A thread ....

#Medtwitter This GIF sums up everything nicely. It tells us three things

1. Statins work
2. More LDL reduction - lower the risk of heart attack, stroke etc
3. More statins/ more powerful statins- more LDL reduction Image
May 24, 2021 • 16 tweets • 3 min read
Let us answer all the questions asked by this Dhongi Baba. I will try and answer 1 or 2 questions every day for the benefit of the general public. Please share so that the falsehood of this person is exposed on a daily basis.

Please retweet with the hashtag #RemoveRamdev.... Answer 1:

First, there is nothing like "Allopathy". Allopathy is a term used by the

Wikipedia says

"The terms were coined in 1810 by the inventor of homeopathy, Samuel Hahnemann. It was originally used by 19th-century homeopaths as a derogatory term for heroic medicine"
May 23, 2021 • 12 tweets • 9 min read
Dear @verified

Please remove the verified status of one Mr Ram Kisan Yadav with the Twitter handle @yogrishiramdev . The person has violated the regulations of @Twitter and @TwitterIndia on several occasions. A suspension may also follow.

#SuspendRamdevfromTwitter These are the policies that this person has violated on several occasions

help.twitter.com/en/managing-yo… Image
Apr 22, 2021 • 25 tweets • 6 min read
Today’s Thread is on #Steroids

@netshrink @IndiaESI @SanjayKalraDr1 @DrAmbrishMithal @AskDrShashank Q. What are steroids ?

Steroids are organic compounds with four rings in a very specific molecular configuration.

They are extensively found in plants and animals
Mar 10, 2021 • 19 tweets • 3 min read
#Medtwitter #ClinicalPearl

This thread will tell you how Quackery works... Step 1: Quacks understand the market needs. If patients find oncology treatment painful and expensive, they will 'create' a product for cancer. Quacks understand entrepreneurship
Mar 9, 2021 • 4 tweets • 1 min read
I actually responded to an in-flight emergency once. I am an Endocrinologist Turns out the patient was diabetic and he was having hypoglycemia. Corrected the same, the patient was better.
Mar 9, 2021 • 5 tweets • 2 min read
#Medtwitter #EndoTwitter #ClinicalPearl

Karyotype must be offered to all women presenting with Premature ovarian insufficiency (POI) There is no age cut-off per se for ordering a karyotype in women with POI. In a study, more than 30% of women with abnormal karyotype were more than 30 years of age!
Mar 9, 2021 • 11 tweets • 2 min read
It's not about what is legal and what is illegal. Everything that is 'legal' is not morally right and everything that is illegal is not morally wrong It's about creating a system that fools thousands of young boys and girls to take up BHMS only to realize that there is little or no market for it when they finish the course
Feb 19, 2021 • 12 tweets • 3 min read
10 Questions for the Honorable Health minister @drharshvardhan (A Thread) Q1. The title of your video says "Release of scientific research paper" . Would like to see the research paper. Can you share the Pubmed link for the paper ?