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There are 30 types of blindness caused by cone-rod dystrophies. Scientist have now created light-detecting cells from skin cells and injected them into 🐁 to partially restore their night vision... @nature #scienceiscool 1/3
The work from @UNTHSC is the first to show mitochondrial-to-nuclear signaling via free-radicals (like powerplants emailing the government) is VIP for cellular reprogramming...2/3 @PBTEXAS go.nature.com/3adnDx0
Their 5-chemical🍸induces free-radicals (mROS) in mitochondria, which activate inflammatory protein NF-kB, which turns on reprogramming genes, which convert skin cells into rod cells for injection 👁️💉 -- proving free-radicals aren't all bad! 3/3
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David Sinclair, PhD
@davidasinclair
There are currently 300+ different genetic versions of #coronavirus. Here's my take on a new study that investigates if they multiply at different rates, at a way to help explain regional & individual differences in #COVID19 ... tinyurl.com/y7bgzvse
Summary: scientists from Zhejiang University studies 11 strains of SARS-CoV-2, from early in the pandemic. They identified mutations, mapped them to protein structures, tested how the #coronavirus multiplied in & killed cells, & compared to patient outcomes... 2/ #COVID19
19 of the 31 identified mutations were novel, despite the relatively early sampling dates, indicating that the true diversity of the viral strains is still largely underappreciated. That's an interesting finding right there... 3/ #COVID2019
Read 8 tweets
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David Sinclair, PhD
@davidasinclair
Some scientists and reporters are saying smoking might protect because you'd expect more smokers in the hospital. Come now. 17 - 46% of smokers lie to their doctors about smoking...
#COVID_19 #FactsMatter #CoronaVirusUpdate tinyurl.com/y7waua22
tinyurl.com/y9mcv9uc ...1/3
Statistics lie and so do patients. Other classic lies include:
* 43% about exercising
* 38% about not drinking alcohol
* 29% about the number of sexual partners
Studies based on questionnaires are flawed...2/3
...@US_FDA warns that smoking makes #Covid_19 symptoms worse. This isn't rocket science. If you can't breathe from #COVID and your lungs are dirty and fibrotic, what do you expect? tinyurl.com/y87p3g2w ...3/3
Read 6 tweets
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David Sinclair, PhD
@davidasinclair
Here’s how PCR tests work, why they are flawed, and why people are retesting positive...
First: how #Covid_19 PCR tests work. It’s 1980s tech, a kid could run one, but if you don’t care, skip down to the flaws...
1. Get a nose or lung mucus/cell sample, deeper the better.
Read 25 tweets

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