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The @US_FDA has given emergency authorization to 6 #COVID19 antibody tests, only one of which is an ELISA. The lateral flow tests, while cheap, have more false-positives and reliability ?s.
covidtestingproject.org/faq.html
nytimes.com/2020/04/24/hea… ....a get what you pay for problem
More perspective on the limitations of @COVID19 antibody testing and what it can help with
by @apoorva_nyc
w/ @nataliexdean @CT_Bergstrom @BillHanage @SaskiaPopescu @mtosterholm nytimes.com/2020/04/26/hea…
The problems with the antibody tests are further exacerbated by the @US_FDA EUA process, unleashing the spread of inaccuracy
politico.com/news/2020/04/2…
@politico by @ZacharyBrennan and @davidalim
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Eric Topol
@EricTopol
If the US did 100 million #COVID19 tests today, it would still not be the best country in the world for testing, as wrongly asserted every day by @POTUS. It will never be. It essentially didn't do any tests for 2 months after its 1st patient. Timing is everything.
More on this topic, since too many people still don't understand its vital importance, from @MaxCRoser @OurWorldInData
It doesn't matter much how many tests are done now, after the spread and damamge is done
You can see all the countries #COVID19 testing as a function of WHEN they started and per 1000 people, from this new, terrific graph @OurWorldInData by @MaxCRoser @EOrtizOspina @JoeHasell @UniofOxford
ourworldindata.org/grapher/total-…
Read 5 tweets
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Eric Topol
@EricTopol
The new remdesivir data from Tony Fauci from N >1,000 placebo-controlled trial (unpublished, Oval Office citation) does not show statistically significant reduction in mortality (8% vs 11%, in the right direction) but a clear-cut benefit in time to recovery 11 vs 15 days, P<0.001
It's been a very confusing story. First a positive signal from compassionate use @NEJM, then @UChicagoMed leak encouraging. Then @lancet today clearly negative trial, underpowered. Then this.
The good news: it looks like we now have a drug w/ some efficacy. And that's very good.
I'm feeling better that the signal I called weeks ago from the 1st report panned out to be true, despite many who challenged the call
Read 6 tweets
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Eric Topol
@EricTopol
Coming down from the plateau a bit.
Best sign I've seen for the US fatality curve in 2 weeks
Please keep coming down
Mitigated by a rise in US cases today, back well over 2,000 again. Let's just hope that's a bad day on the way to better ones. Still very concerned about states that are now/soon opening leading to a rebound.
That graph @COVID19Tracking is on deaths, not cases, as I mistakenly wrote above.
Read 4 tweets

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