Thread by @hkumed

A team from @hkumed studied how #SarsCoV2 infects and multiplies in human lung tissues. The study compared the virus with SARS-CoV, the #coronavirus responsible for the 2003 SARS outbreak, on how they attacked human lung tissue. #COVID19

Key takeaways from the study:

► #SarsCoV2 and SARS-CoV infected the same types of cells in the lungs.
► #SarsCoV2 was more capable of infecting lung tissue than SARS-CoV. #COVID19

► Once infected, #SarsCoV2 multiplied 3.2 times faster than SARS-CoV in 48 hours, explaining the rapid spread of the virus during the early stages of infection.
► The immune system had a poor response to #SarsCoV2, which allowed this virus to infect and multiply better.#COVID19

For more on the study - Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19: academic.oup.com/cid/advance-ar…

#COVID19