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A team from @hkumed studied how #SarsCoV2 infects and multiplies in human lung tissues. The study compared the virus with SARS-CoV, the #coronavirus responsible for the 2003 SARS outbreak, on how they attacked human lung tissue. #COVID19 Image
Key takeaways from the study:

► #SarsCoV2 and SARS-CoV infected the same types of cells in the lungs.
► #SarsCoV2 was more capable of infecting lung tissue than SARS-CoV. #COVID19
► Once infected, #SarsCoV2 multiplied 3.2 times faster than SARS-CoV in 48 hours, explaining the rapid spread of the virus during the early stages of infection.
► The immune system had a poor response to #SarsCoV2, which allowed this virus to infect and multiply better.#COVID19
For more on the study - Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19: academic.oup.com/cid/advance-ar…

#COVID19
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#SarsCoV2 #coronavirus #COVID19

More from @hkumed see all

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HKU Medicine
@hkumed
Q: Are higher temperatures more likely to cause loss of infectivity in #SARS_COV_2?

A: The team at @hkumed incubated the virus and observed how long it would take for it to lose infectivity at different temperatures. #COVID19 #KnowTheFacts
Q: Do different surfaces have an effect on the amount of time it takes for #SARS_COV_2 to lose infectivity?

A: The team @hkumed tested how long it would take for the virus to lose infectivity on different surfaces. #COVID19 #KnowTheFacts
Q: Are disinfectants effective in causing #SARS_COV_2 to lose infectivity?

A: The @hkumed team tested a wide variety of different disinfectants and found that all the following were effective in causing viruses to lose infectivity after 5 minutes of use. #COVID19 #KnowTheFacts
Read 4 tweets
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HKU Medicine
@hkumed
Q: Can we sanitise and reuse masks to expand its lifespan?

A: We cannot sanitise and reuse masks. If you want to extend its lifespan, cut a piece of gauze and line the inner part to prevent direct contact of the mask to your mouth and nose.

#knowthefacts #COVID19 Image
Q: Would wearing multiple masks improve the effectiveness of the filtration?

A: The key to effective filtration is the fit of the mask. Wearing multiple masks will affect its fit and obstruct your breathing.

#knowthefacts #COVID19 Image
Q: Is it possible to protect yourself with towels?

A: Towels and scarves can prevent direct contact of droplets onto your nose and mouth to a limited extent, but are not effective in protecting yourself against the new #coronavirus.

#knowthefacts #COVID19 Image
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