The annual SARI hospitalization incidence ranges from 325-617/ 100,000 population in South Africa. Do we know the incidence of #SARI for south Asian countries?
Assuming the least incidence of 325/100,000 for India: 4.22 crore new cases admitted each year. Although it can be higher and has a bimodal seasonal presentation, a simplistic assumption of the monthly burden will be 32 million. Do we have these many SARI cases reported?
With these estimates, nearly 50-270 per 100 k population might be getting admitted with SARI each month. If districts are not reporting even one SARI cases as of now, this is concerning. Among others, the proportion of #COVID19 positivity as of now should guide lockdown release.
Each district should start reporting SARI cases. Obsession with testing is masking the importance of surveillance: States & center can start reviewing SARI & ILI surveillance at each district/ subdistrict level. #Covid19 Testing in these should guide actions.
As of now, we do not know which districts haven't reported SARI? Which districts have covid19 + among SARI, not reported but SARI +ve for covid19?
Also, which districts have more than expected ILI cases? What % of ILI are tested positive for covid19, and in which districts?
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However mild #Omicron is, it is not a vaccine. There are deaths and hospitalizations due to this variant.
Stay away from misinformation.
Compared to Vaccination, natural infection could not protect population (against death or hospitalization) against any variant (Alpha, Beta, Gamma or Delta).
Proponents of Herd immunity are saying it again; #Omicron would provide herd immunity.
Evidence matters, not opinions
During delta wave, this is what we knew based on #Epidemiology of infectious diseases.
-This is not the last variant.
-There will be another wave.
More actions points can be following :- 1. Since day of 1st case of #Omicron#B.1.1.529, establish travel history & identify secondary transmission throughout world. If primary case was in early November, not difficult to miss areas of circulation.
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2. Botswana, South Africa & Hong Kong cannot be the only areas where #Omicron has travelled. These areas are the ones that have probably better surveillance and genomic sequencing and hence have reported in timely manner. Absence of reporting is not absence of circulation.
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3. Imposing travel restrictions, restricting entry from few countries is NOT going to help either prevent or control the spread of #Omicron. It’s akin to closing stable door after horse has bolted. Instead, identify cluster of cases of recent origin & do genomic sequencing.
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Brilliant study done in China, If scaled up, blood pressure reduction (-26.3 mmHg) achieved by training lay health workers can reduce significant mortality in LMICs.
-Globally, >17.9 million people die each year CVDs.
-Hypertension related CVDs contribute a significant proportion
-Chinese study shows some of these deaths & disability are preventable.
-Train lay village workers in BP measurement, counseling & provide affordable drugs.
Sudden cardiac arrest & Sudden cardiac death (SCD) refer to the sudden cessation of cardiac activity with hemodynamic collapse, typically due to sustained ventricular tachycardia/ventricular fibrillation; mostly occur in patients with previously undiagnosed diseaes.
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Results from Framingham heart study suggests that more men are affected with increasing age.
Not rare, 15 percent of the total mortality in the United States & other developed nations is due to SCD. (pubmed.ncbi.nlm.nih.gov/11684624/)
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-It is the initial clinical manifestation of 15% of coronary heart diseases (CHD).
-SCD is the mechanism of death in over 60% of patients with known CHD.
-Risk increases by a number of factors: Age, underlying cardiac diseases, post-menopausal women, CHD risk factors
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This tweet thread is about the results from the second serosurvey done in the #Karnataka state. Ahead of sharing the link, some caveats first. 1. The @DHFWKA has used the data from this round of serosurvey in late March to update testing and surveillance strategies.
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2. The study found Lower levels of IgG seroprevalence, mostly due to antibody waning. 3. A substudy was done to confirm the antibody waning. This study was delayed due to rapid surge of cases in April. 4. We found near 0 prevalence of active cases during mid-February 2021.
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5. There was a subsequent surge seen in Karnataka state due to a mix of alpha, delta which was picking up speed in April, and a large susceptible population were infected. 6. Results from the substudy on antibody waning was necessary for releasing the final report & paper.
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Polio anywhere could be a threat to countries that had eradicated it. It took decades to eradicate polio in most parts while some are yet to eradicate. Not just this necessity, it was possible mostly due to a collaborative approach & strong leadership at the global level. 1/N
Lessons from Polio Eradiation, Cochi S et al
-Strong political & social support in each country
-Strategic planning & policy development
-Partnership management & donor coordination
-Program operations & tactics
-Oversight and independent monitoring.
If there was high polio circulation in one region, other countries could prevent the possibilities of its import by vaccinating the children in their countreis. Therefore, all countries are continuing polio vaccination till other regions accomplish eradication.
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