Treatment for Mod to Severe cases
May need oxygen as they tend to be happy hypoxics with low O2 saturation,florid pneumonia,high fever,breathlessness,possible cytokine storm(raised inflammatory markers like LDH,Sr Ferritin,Ddimer,CRP)
#coronavirus
#COVID19
Tocilizumab
Immunosuppressant (40-60000/dose),mainly used in Rheumatoid arthritis
Humanized monoclonal antibodies against Interleukin 6
Used in high risk cases with good success in municipal hospitals in Mumbai,patients with breathlessness,pneumonia,Cytokine storm
Itolizumab
Humanized IgG1 monoclonal antibodies against CD6 receptors
Commonly used for psoriasis, arthritis
Used In high risk cases
Results to be available end june,early july
Company - Biocon
@Bioconlimited
Developed by Gilead lifesciences
Form of lyophilized powder for injection
1st used for Ebola in 2014
Gilead signed deals with Cipla,Hetero,Mylan,Jubilant for India,Pakistan
Used for severe cases
Drug controller authority India recommends 5 day course of Rx
Mixed results for mild to moderate cases
Tablet form,inhibits viral replication
Price 3000 for 34 tablets
Developed by Japans Fujifilm Toyama Chemical Ltd
Marketed by Glenmark
Covifor
Injectable 100mg IV dose
Company Heteropharma
Cost 5-6000/dose ,6doses
Plans to unload 60,000-70,000 injections of Remdesivir in 1 month, price fixed at 4000/dose
Ritonavir,Lopinavir
Mainly used in HIV
supposedly decrease mortality in severe cases,often used as combination therapy with other drugs
@realDonaldTrump favourite Hydroxychloroquine
Antibiotics- Doxycycline, Azithromycin ,Augmentin,Ceplalosporins to prevent bacterial infections in severe cases,where corticosteroids are given
Ivermectin
@unseenvalue @punitbansal14 @joshikshitij99 @thescorpionphil