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Q: Are higher #temperatures more likely to cause loss of infectivity in #SARSCoV2?

A: @hkumed researchers incubated the virus and observed how long it would take for it to lose infectivity at different temperatures.

#COVID19 #KnowTheFacts
Q: Do different #surfaces affect the time it takes for #SARSCoV2 to lose infectivity?

A: Team from @hkumed tested how long it would take for the virus to lose infectivity on different surfaces.

#COVID19 #KnowTheFacts
Q: Are #disinfectants effective in causing #SARSCoV2 to lose infectivity?

A: @hkumed tested a wide variety of different disinfectants and found that all the following were effective in causing viruses to lose infectivity after 5 minutes of use.

#COVID19 #KnowTheFacts
For more on the study by Professor Leo Poon, Professor Malik Peiris of @hkumed & others:
thelancet.com/journals/lanmi…
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Related hashtags

#temperatures #SARSCoV2 #COVID19 #KnowTheFacts #surfaces #disinfectants

More from @hkumed see all

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HKU Medicine
@hkumed
An @HKUMed study examined the use of surgical masks to prevent #SARSCoV2 transmission in hamsters. It found that using a mask reduces not only the risk of infection, but also the severity of the disease.

(1/5) #COVID19
Method:

Healthy and infected hamsters were housed in separate cages placed next to each other.

A surgical mask partition was placed on either side to separate the cages, with air flowing from the infected side to the healthy side.

(2/5) #COVID19
Key takeaways:

🐹 No mask barrier: 66.7% (10 of 15) of healthy hamsters were infected
🐹 Barrier on infected side: 16.7% (2 of 12) were infected
🐹 Barrier on healthy side: 33.3% (4 of 12) were infected

(3/5) #COVID19
Read 5 tweets
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HKU Medicine
@hkumed
An @hkumed study found that #SARSCoV2 can multiply rapidly in lab-grown bat intestinal cells, suggesting these cells could be used to study SARS-CoV-2 infection and bat viruses;

It also studied how the virus infect human intestinal cells and spread via the gut.

(1/5) #COVID19
Key takeaways:

🦇 Intestinal cells from both bats & humans were easily infected by #SARSCoV2
🦇 Enterocytes (intestinal cells involved in digestion) were the virus's main target

(2/5) #COVID19
Key takeaways (cont'd):

🦇 Infected intestinal cells developed cytopathic effect (structural changes due to viral infection) and broke over time, releasing large quantities of virus;
🦇 Cytopathic effect developed sooner in humans than in bats

(3/5) #COVID19
Read 5 tweets
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HKU Medicine
@hkumed
The amount of #SARSCoV2 detected in #COVID19 patients was the highest in the first week when symptoms appeared, according to an @HKUMed study, which analysed saliva samples from 23 lab-confirmed patients to track their viral load as the disease progressed. (1/4)
They also studied immune response through blood samples.

Antibodies were detected 10 days after symptom onset and the viral load gradually declined as more antibodies were produced; but the virus was still detectable in a third of #COVID19 patients studied after 3 weeks. (2/4)
Key takeaways:

▶️ Median time between symptom onset to hospitalisation was 4 days
▶️ Older #COVID19 patients & those with severe disease had a higher viral load
▶️ Underlying chronic illness did not affect the viral load of #SARSCoV2

(3/4)
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