Antiviral activity of an alcoholic hand disinfectant. Comparison of the in vitro suspension test with in vivo experiments on hands, and on individual fingertips.
[from 1983] sciencedirect.com/science/articl…
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[from 1983] sciencedirect.com/science/articl…
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"The significance of 'spontaneous decay', in our view, is that it marks a qualitative difference between the 'reality' of hand disinfection and its model, the suspension test.
It also underlines the difference between enveloped and naked viruses in...
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It also underlines the difference between enveloped and naked viruses in...
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..the hand disinfection situation"
"As to the cause of 'spontaneous decay', one may speculate that the chemical milieu of the skin surface, e.g., pH or fatty acids, contributed to inactivating virions, predominantly those with a lipid-containing envelope.
In addition,..
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"As to the cause of 'spontaneous decay', one may speculate that the chemical milieu of the skin surface, e.g., pH or fatty acids, contributed to inactivating virions, predominantly those with a lipid-containing envelope.
In addition,..
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..might have mechanically destroyed virions, this hypothesis being supported by the fact that subjectively more rubbing per skin surface area occurred in the finger test than in the hand test, and enveloped viruses were more inactivated in the controls of..
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..the finger test than of the hand test."
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