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@MackayIM

9 Oct

Antiviral activity of an alcoholic hand disinfectant. Comparison of the in vitro suspension test with in vivo experiments on hands, and on individual fingertips.
[from 1983] sciencedirect.com/science/articl…
1/

"The significance of 'spontaneous decay', in our view, is that it marks a qualitative difference between the 'reality' of hand disinfection and its model, the suspension test.
It also underlines the difference between enveloped and naked viruses in...
2/

..the hand disinfection situation"

"As to the cause of 'spontaneous decay', one may speculate that the chemical milieu of the skin surface, e.g., pH or fatty acids, contributed to inactivating virions, predominantly those with a lipid-containing envelope.
In addition,..
3/

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ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻

@MackayIM

5 Oct

Fears about spreading COVID-19 at the beach 'overblown'
smh.com.au/national/fears…
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Outdoors is better than indoors when considering the risk of infection by SARS-CoV-2.
Dilution of aerosols outdoors & their removal via wind occurs much more easily outdoors than in a closed room especially if that room has no air filtration or active air exchange.
*But* ...
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...that doesn't mean proximity to an infected person & time exposed to them aren't still really important.
We need to keep our distance from others who may be infected and not spend too long indoors or near those outside our "bubbles".
3/

Read 4 tweets

ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻

@MackayIM

4 Oct

"Get a test when sick, and isolate while you await your result"
There's something missing from this message and it's
"*stay* isolated, even if your SARS-CoV-2 test is negative because you're still sick with *something* infectious!"
I don't want it. Others don't want it.
1/

I really feel like this part of the message needs to be stressed otherwise I don't think we're going to learn from the benefits of adopting masks in traditionally mask-phobic countries.
If not, we're just going to stumble back into flu season (also RSV, MPV etc) deaths and
2/

hospitalizations because somehow they're..."okay" deaths? But that was a pandemic! Seasonal illness & death is just 'normal', silly.
..then we're all idiots!
We've shown we *can* reduce morbidity & mortality due to other viruses, not just SARS-CoV-2
/3

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ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻

@MackayIM

28 Sep

Some thoughts on wastewater (sewage) testing...
💩Usefulness?
Of most benefit when used in an area with no known cases. Lets us look for a signal that virus is somewhere in that region. Pop-up testing may then be deployed to get a better idea of the situation

💩Mature technology?
Methods/usefulness still being evaluated.
What does a positive mean? How often are false negative/positives likely? Which PCR-based tests are best? What processes in place to confirm wastewater positive result & what response will that trigger if confirmed?

💩Do all agree?
Full spectrum of responses to wastewater testing, from exuberance to dismissal. I think time and continued refinement of the methods will tell which was the best position. As with everything in this pandemic, we're learning many new things as we go.

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ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻

@MackayIM

23 Sep

COVID-19 epidemiology reports, Australia, 2020
-latest report with data up to 13SEPT2020
🦠"The global case fatality rate (CFR) is approximately 3.2% and is decreasing as case identification improves"
🦠674/26,753 detected cases (2.5%) were fatal
www1.health.gov.au/internet/main/…

🦠44% of 12,636 cases (47% of all recorded COVID-19 cases in Australia) had fever, 63% had cough, 39% had sore throat, 25% had runny nose - all in a wide range of combinations

🦠Most of the past month's 36 sequenced genomes from New South Wales, Queensland and South Australia belong to B.1.1.25 lineage. Other different sporadically detected lineages likely represent travel-introduced variants

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ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻

@MackayIM

23 Sep

@WHO

At #UNGA 75 @WHO has 3 messages to share:
1⃣ Need for equitable access to #COVID19 tools
2⃣ Maintain the momentum towards achieving the sustainable development goals
3⃣ Call to prepare for the next pandemic together, now

@WHO

1⃣ At #UNGA , @WHO calls on 🌐 leaders to support the Access to #COVID19 Tools (ACT)-Accelerator, a unique international collaboration to fast-track the development, production & equitable access to tests, treatments, & vaccines globally, while strengthening health systems.

@WHO

2⃣ #COVID19 risks unravelling decades of gains made in health & development. At #UNGA , @WHO stresses the need to invest in stronger health & data systems to achieve universal health coverage & to meet the health-related targets of the sustainable development goals

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More from @MackayIM

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ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻

ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻

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