🚬Smoking increases 10x the risk of ESKD in #IgAN#Kidneywk
Steroids are no walk in the park in #IgAN. With very good supporting care loss of kidney function is very mild (-1.6 ml/min/year). Testing had to be terminated prematurely due to adverse events. #KidneyWk
10 year follow up of #STOPIgA. No differences. And now with #SGLT2i or hydroxichloroquine thess curves may separate without the use of steroids. #KidneyWk
Fluid overload is bad news for patients: 1. Causes AKI 2. Prevents organ and patient recovery 3. Increases mortality
Ill share some of the data masterfully presented by @criticalbeansmd today at #KidneyWk starting with the take home points, in case this is the only tweet you see
Fluid Overload is very common, is all over the place and it has several definitios.
Patients accumulate weight at least for the first 7 days if the ICU doesn’t have some sort of FLUID STEWARDSHIP program in place. Remember fluids are drugs #KidneyWk.
There is no single situation in which Fluid overload is beneficial for patients. On the contrary. It is bad in every situation, doesnt matter how we slice or present the data. Liberal fluid strategies are always worse #KidneyWk
All nephrologists should be learning #POCUS now. It is safe, reproducible, cheap!!! Some uses are: 1. Rule out obstruction 2. Dx cause of hemodynamic inestability 3. To guide vascular access
Beyon the basic applications in #AKI 1. Assessment of kidney perfussion 2. Detection of early AKI 3. Prediction ofpersistent AKI 4. Detect kidney congestion
2D US is ok, but using other modalities like doppler we can get more granular data on kidney hemodynamics.
Dr. Jardine on side effects of SGLT2i. Where is evidence coming from? #Kidneywk
Mostly is coming from CREDECE since it has the largest population of advanced CKD. Side effects are not different across different stages of CKD #Kidneywk
Hypoglycaemia not common, about 1%. DKA is rare (1 case per 1000 users) but real mostly seen in people who require insulin. #kidneywk