A criticism of the data regarding children and #COVID19 from the first surge is that it was acquired with schools closed

Its now surge 2 and they're open

Let's look at the up to date info from @PHE_uk and @ONS infection survey and see what is going on

#schoolsreopening

1/10
After an initial surge, in the recent weeks of @PHE_uk data we have seen a decline in cases in the 10 - 19y age group

Otherwise lowest cases remain in the 0 - 10y ages, although still trending up

assets.publishing.service.gov.uk/government/upl…

2/10
What about school outbreaks?

They've been flat for the past several weeks despite rising prevalence in the community

Unfortunately doesn't tell us about how many cases involved or whether it's children or staff/teachers

assets.publishing.service.gov.uk/government/upl…

3/10
People will rightly point out that these probably underestimate the case numbers, due to less symptoms or asymptomatic infections in children

The @ONS infection survey overcomes this by testing *randomly* at large scale

Let's see what's going on there...

4/10
Primary school age children among the lowest prevalence despite full time in person schooling

Secondary age however has high prevalence, although also showing signs of flattening/decline; either following trend in young adults, or half term related

ons.gov.uk/peoplepopulati…

5/10
This more or less mirrors what we expect from existing data

Primary school age much lower risk, teenagers higher risk

How much secondary transmission is *in schools* as opposed to from the community is unclear, but hopefully we will have more data soon

6/10
But were initial increases in cases due to schools reopening?

No

We'd expect a 2 -3 week lag if they were due to schools (red arrow)

Cases were already increasing by week 36 *before* schools opened

Schools will have added to an existing increase, but did not cause it

7/10
The trend has been:

Rapid increase in young adults/older teens - they are to COVID-19 what kiddies are to flu

This leaks into secondary age children and adults

Primary age children get dragged up behind along with older adults

8/10
What about teachers?

It is vital we ensure our key workers are kept safe whilst providing essential services

No sign of any increased risk for teachers compared to other key workers so far - good news

ons.gov.uk/peoplepopulati…

9/10
Summary

In periods of high prevalence:
-primary schools still low risk
-secondary age children higher risk
-whether cases are transmitted in school or elsewhere is unclear
-community infection rates drive school infections

Keep community rates low to prevent outbreaks

10/10

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More from @apsmunro

13 Oct
Quick thread on latest @ONS infection survey data, which is very informative!

FYI: the survey involves mass random population testing for #COVID19 in England and Wales, so is not biased by symptoms/test seeking - so very useful indeed!

1/7
I can't go any further without pointing out the massive regional disparities between the north and south of England

Whilst not completely straight forward, this is likely in part due to socioeconomic differences which we know influence effects of disease transmission

2/7
But of course, I'm interested in the KIDS!

Schools open for nearly 6 weeks with fairly limited infection mitigation, and cases rising exponentially across the country

What's happening with primary school age kids?

Not much at all

Even I am surprised about that

3/7
Read 7 tweets
1 Oct
"If there's one thing we learn from history, it's that we don't learn from history"

A new study from India looks at #COVID19 contact tracing

And now reported, "[children] transmitted the virus at rates similar to the rest of the population"

🤔

latimes.com/world-nation/s…

1/10
There is SO much to dig in to here because these findings are complex - but we'll stick with the major issues for now

Child index cases were found to have a high proportion of positive contact of the same age

They must infect them easily, right?

science.sciencemag.org/content/early/…

2/10
The first caveat, is that to be defined as a index case, the child was almost certainly symptomatic

Symptomatic people seem to be much more infectious than asymptomatic

A large proportion of children seem asymptomatic (~50%) so findings are not generalisable

But wait...

3/10
Read 10 tweets
25 Sep
🔥Hot off the press🔥

New article in @JAMAPediatrics from me and @SaulFaust

"The education and well-being of the current generation of children and young people should be the highest priority in any national strategy to reopen society."

jamanetwork.com/journals/jamap…

1/8
Children have been spared the worst of disease from the pandemic, even considering the extremely rare post-COVID-19 hyperinflammatory syndrome

But school closures have been harming children, so the question regarding their role in transmission has loomed large

2/8
A new study from brings us a step closer to understanding

In a meta analysis of contact tracing studies, children acquire the infection less than adults. Looking at household transmission specifically, by less than half (OR 0.41, 95%CI 0.22 - 0.76)

jamanetwork.com/journals/jamap…

3/8
Read 8 tweets
21 Sep
Fascinating

2 groups of scientists with opposing viewpoints on handling the pandemic write open letters to the chief medical officers

Strangely I found them both compelling, and agree with the majority of both letters

Links in following tweets

1/4
First a group recommending more acknowledgment of non-COVID harms of interventions, and recognition of the age disparity in risk for future interventions



2/4
Next a group recommending strong virus suppression with sustainable measures, and arguing against age stratified intervention



3/4
Read 4 tweets
15 Sep
There has never been more confusion about the role of children in transmission of #SARSCoV2 , and tensions are running high over implications for #schoolsreopening

Time for some clarity

@Damian_Roland and I review ALL the evidence on @DFTBubbles

dontforgetthebubbles.com/the-missing-li…

1/13
When considering transmission risk we must consider 2 classes of factors;

Non-modifiable: The biology of the host and pathogen

Modifiable: Behavioural or environmental influence

Since we can change the latter via policy/guidance etc, we'll focus on the former

2/13
How easily to children catch the virus?

Household contact tracing studies suggest less easily than adults; by about half given the same exposure, based on 4 reviews of all the evidence (links in next tweet)

3/13 ImageImageImageImage
Read 13 tweets
14 Sep
I've almost given up on any balanced discourse about children, #COVID19 and schools, as everyone seems intent on either pretending children are not affected at all, or becoming borderline hysterical over the point

Case study: US daycares

1/6
This study from daycares in Utah has been amplified by high profile figures on twitter as a "big deal"

12 children infected (by staff) with 12 secondary cases, all in their homes, with no mention of transmission in the facility

A "big deal" 🤯

cdc.gov/mmwr/volumes/6…

2/6
That study is 3 days old and has an altmetric score of over 4000

That is insane

12 children with 12 secondary cases in over 3 months

How is this even newsworthy?

3/6
Read 6 tweets

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