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Eric Topol Profile picture
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9 Nov, 4 tweets, 3 min read
The big news is that we have a #SARSCoV2 vaccine with a strong signal of efficacy. Perhaps as high as 90% with 94 events at an interim analysis. Well below 50-60% FDA/WHO threshold. That's exciting!
wsj.com/articles/covid…
Oops. Above not below.
Application for FDA Emergency authorization can be filed when safety timetable is met. We'll have at least one vaccine into Phase 1a rollout before year end which is a stunning achievement-- from virus sequence to vaccination in < 12 months.
Yes, this is a "historical moment"
nytimes.com/2020/11/09/hea…
by @katie_thomas @carlzimmer
w/@VirusesImmunity @SaadOmer3 @DrPaulOffit
“The results are really quite good, I mean extraordinary” --Tony Fauci.
washingtonpost.com/health/2020/11… @Carolynyjohnson

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More from @EricTopol

Eric Topol Profile picture
10 Nov
What does runaway spread look like? Image
Leading to an unprecedented number of hospitalizations
Today, more than 60,000 Americans are hospitalized with covid
Read 4 tweets
Eric Topol Profile picture
7 Nov
Not to detract from the celebration BUT
We just had >128,000 new US infections, another new record.
The hospitalizations continue to rise to almost 59,000 ()(~1,000 more since yesterday)
1,097 more people died.
@COVID19Tracking
We have serious work cut out for us
We're about to go to a new pandemic peak in people hospitalized, >60,000
The rise in cases is limitless unless we take aggressive action, which of course should have been initiated months ago. But it's never too late.
Read 4 tweets
Eric Topol Profile picture
4 Nov
Over 100,000 new covid cases today (1st time here or anywhere in the world), more than 1,200 deaths, hospitalizations relentlessly climbing to a new pandemic peak.
Might be a good time for a new strategy. Like having a plan.
washingtonpost.com/nation/2020/11…
The virus is thriving finding new hosts, making them sick, and killing them. And the pattern is all too familiar.
1. Most new infections for the pandemic, >103,000, on a very steep ascent now
@COVID19Tracking
2. As cases rise, so do hospitalizations
Read 4 tweets
Eric Topol Profile picture
4 Nov
"Voters were deeply divided on what mattered more: containing the coronavirus or hustling to rebuild the economy"
As if this was a dilemma rather than it being fully interdependent.
If C contained, E expands.

Source for quote nytimes.com/live/2020/11/0…
This false dichotomy is the 2020 version of "It's the economy, stupid."
Read 4 tweets
Eric Topol Profile picture
31 Oct
Today marks 11 years on @twitter for me.
Thanks for reading along🙏
I wrote a 🧵about what I learned in the first decade here:

This one is about what I learned this year, a most challenging one for all of us 1/
For 10 years, I posted biomedical and science stuff mainly about genomics, digital medicine, #AI. As the pandemic became a reality in February, I shifted attention to it, almost exclusively 2/
I'd already been tweeting too much (aka twitterrhea, and sorry for that), but this led to more than doubling or even tripling the posts on any given day due to the outpouring of new information (ideal substrate for an info junkie) 3/
Read 14 tweets
Eric Topol Profile picture
27 Oct
I wish all these déjà vu reports of "disappearing antibodies" would disappear. That is not a problem.
directorsblog.nih.gov/2020/10/20/two… by @NIHDirector
nejm.org/doi/full/10.10…
@NEJM
See @florian_krammer's great thread explanation
Or this paper on the known knowns
jimmunol.org/content/early/…
Read 4 tweets

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