Elisabeth Bik is a VERY hard woman. I thought she was outing these for "A" and "C" not being differently treated rats, different _slides_, but actually the same slide flipped upside down.

I thought B was actually different.

But then...
.... I saw this too
Remember, do not mock basic science papers for having this level of fakery.
Praise them for outing themselves in this way.

They show that when a scientist says the average amount of RED or GREEN or WHITE differs between different treatments, they may have just been marking different "regions of interest" on the same slide!
In clinical research we do not show our raw data.

If I drew round different parts of the heart to measure T3 or T4*, and then claimed that disease X, or post disease X syndrome was different from a control group, you would have NO chance to spot my cheekiness.
These cases of self-destructing basic science papers are a reason to be EVEN MORE fearful of clinical research papers.

So watch @DrJHoward's AHA presentation of SAMSON today with great care. He purports to show individual patient data, but are they all different?
Build up your skills in clinical trial result interpretation through this course in simple 15-minute seminars!

Still available free:

tweetorials.inspirion.org/h2/2e0014e2e8b…

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More from @ProfDFrancis

15 Nov
Well, I would like to complain about "STATINS".

If you told me you were prescribing me a "STATIN", I would refuse to take it.
Atorvastatin
Simvastatin
Rosuvastatin
Pravastatin
etc.

they are

VASTATINs, not STATINs.
Would you take this statin?
Read 8 tweets
1 Nov
Are these the outfit whose big-deal Covid model was "Oh, it goes up, then it comes down, so let's just say it is a Normal Distribution!"

If so, I am not surprised at anything they do!

It would be like asking why a puppy is chasing its tail.

Just watch, and enjoy the fun!
As for how effective masks are, I guess they just make up some sort of reduction factor, and model what that does to the spread.

Not terribly exciting. That factor is very uncertain, and it doesn't take a genius to realise that a really small reduction will not contribute much.
Read 6 tweets
1 Nov
Josh isn't the first person to think of this, merely the last.
Why don't we have such studies?
Who does studies like that? RCTs?
Read 60 tweets
1 Nov
Both John Mandrola and Vinay Prasad are angry about this study in JAMA. Image
I thought I might join in and give the study a bashing. Image
Read 35 tweets
31 Oct
Great question from Pranev Sharma
Personally I have led a charmed life and never been bullied at work.

But as a TPD this is something I am determined to uncover and eradicate.

When I was a junior doctor, we always assumed that if anyone complained about anything "the old bastards will shaft you forever".
But now we once-registrars have become consultants, we realise we are the same people and

(a) Old gits don't actually shaft anyone - they can't be bothered and indeed have no levers for it: nobody cares what some old git says about someone, when making appointments.
Read 8 tweets
30 Oct
Hidden camera reveals Donald Trump's interaction with Billy Bush.

The really shocking thing wasn't that the Great Leader is a sickening thug, but how a human being can think this behaviour is "benign".

Well done to 2 people for being patient enough to explain it to him, slowly. Image
We need more people like Lena M and Jay Deaz.

Not minimizing or accepting vile behaviour, now has a name, although it is embarrassing that it needs one in a civilized society.

"Active Bystander"

For people who feebly claim that they don't know what to do, there are 4 hints:
Read 9 tweets

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