Thread by @EricTopol

Very exciting to see 94% efficacy of @moderna_tx #SARSCoV2 vaccine at interim analysis of 95 events. This replication of Pfizer's high efficacy tells us the virus is eminently vaccinatable. investors.modernatx.com/news-releases/…

Before year's end we will have at least 2 vaccines with EUAs to proceed with Phase 1a rollout, a historic science achievement in < 12 months. For context:

https://twitter.com/EricTopol/status/1326245544948215808

The replication is independent. A separate Data & Safety monitoring board of Operation Warp Speed did the review. Yes, it's another mRNA vaccine, but it's the same target, the spike protein, shared by the other Phase 3 vaccine programs. They should all work well. We need them too

All the more reason to get hyper-aggressive with a virus out-of-control in the US right now. It is only a matter of months when we start to see this bleak picture turned around. Ultimately, covid-19 illness and fatalities will be largely preventable.

There's other good news today about @moderna_tx's vaccine. It won't require deep freeze (-70°C) logistics. It's stable for 30 days w/ refrigeration. Also this trial had better minority representation. There were 11 severe infections among endpoints, all in the placebo arm.