Such pleasure join @louiseckenny @LivUni Prof Dame Janet Beer & colleagues this evening & a great title for series “Science & Society”. Thank you invitation Q&A. Hope did not offend but think it will by points difference end of season @Everton 
Quick summary - A: Thoughts on COVID & 2020. Drivers epidemics: Ecological & environment change, changes human:animal interface, urbanisation, travel & trade, neglect of public health, undermining of institutions & geopolitics. All features which will define 21stC.
B: Multiple warnings - Nipah, SARS-1, H5N1, H1N1, Zika, MERS, Ebola, Dengue, Chik, & many others. Epidemics becoming more frequent and more complex. Epidemics invariably have an inequitable impact, amplify & increase existing fault lines in societies.
C: Lead to four overlapping or concentric circles of impact i) Direct health consequences ii) Indirect health consequences iii) Economics, Trade, Education, Jobs, Debt, Trust between Governed & Governing and iv) Geopolitics wellcome.org/news/our-respo…
D: Way thru & out of pandemic is by changing fundamentals of the infection. We have to support the economy, jobs, trade. Spending trillions to do so is critical but is only sticking plaster. Until we change the fundamentals there is no exit. Too slow to invest in the true exit.
E: Only way to change the fundamentals is through holistic investment & approach to science: Social Sciences, Behaviour, Trust, Transparency, Diagnostics, Treatment, Oxygen, PPE, Vaccines & the data & health systems to deliver these tools. We need all these, not just one.
F: This will have major implications for science & sciences role in society. For Open Science & the role of the public sector in support the critical tools that are needed, particularly when there is on commercial driver, but which society critical needs.
G: Global scientific community done remarkable job, working in partnerships across borders & disciplines, sharing data,results & more. International partnerships been fundamental. Optimistically incredible progress in 2020 will catalyse a new way of working in the years to come
H: Over last decade we may have stared into the abyss of nationalism. COVID & great challenges of 21stC show how dangerous that is & will be. From epidemics, to drug resistance, to climate change, energy, water, food, others - none can be addressed with a nationalistic approach
I: You cannot turn on public health, health systems, trust, partnerships or institutions when you might need them. They need investment over years, investment in people, infrastructure & sharing ideas. It is investment over years that provides the resilience when a crisis comes
Ii) Invariably international partnership forged outside or between crisis that will be best placed respond in crisis @WHO @rd_blueprint @gavi @CEPIvaccines @UNITAID @ISARIC1 @GlobalFund @FINDdx @GloPID_R @GESDAglobal @SSHAP_action @DFID_UK @EU_Commission @CDCgov & many others
J: Learn lessons 2020: inequality,tensions within & between societies,diversity & inclusion,work patterns & work:life balance,benefits informal work interactions/benefits we cannot measure,flexibility,balance resilience vs efficiency, investment public services & institutions
K: Lastly - Wellcome's commitment to research culture, diversity & inclusion, how we do things as well as what we do, careers, early & mid researchers, people & teams, a research environment that is welcoming & allows us all to be & bring ourselves
L: With a focus & commitment from @wellcometrust to Discovery Research, Infections, Mental Health & the Impact Climate Change on Health. wellcome.org/reports/wellco…
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